Astrocyte-mediated spike-timing-dependent long-term depression modulates synaptic properties in the developing cortex

Astrocytes have been shown to modulate synaptic transmission and plasticity in specific cortical synapses, but our understanding of the underlying molecular and cellular mechanisms remains limited. Here we present a new biophysicochemical model of a somatosensory cortical layer 4 to layer 2/3 synaps...

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