Genome-wide association study identifies 16 genomic regions associated with circulating cytokines at birth

Circulating inflammatory markers are essential to human health and disease, and they are often dysregulated or malfunctioning in cancers as well as in cardiovascular, metabolic, immunologic and neuropsychiatric disorders. However, the genetic contribution to the physiological variation of levels of...

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Veröffentlicht in:	PLoS genetics 2020-11, Vol.16 (11), p.e1009163-e1009163
Hauptverfasser:	Wang, Yunpeng, Nudel, Ron, Benros, Michael E, Skogstrand, Kristin, Fishilevich, Simon, Lancet, Doron, Sun, Jiangming, Hougaard, David M, Andreassen, Ole A, Mortensen, Preben Bo, Buil, Alfonso, Hansen, Thomas F, Thompson, Wesley K, Werge, Thomas
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Anorexia Attention deficit hyperactivity disorder Autism Biological markers Biology and Life Sciences Biomarkers - blood Bipolar disorder Blood Brain-derived neurotrophic factor C-reactive protein Calcium-binding protein CCL17 protein Chemokines Cohort Studies Cytokines Cytokines - blood Cytokines - genetics Cytokines - immunology Denmark Disease Enhancer Elements, Genetic - genetics Erythropoietin Estimates Female Genetic aspects Genetic diversity Genetic Predisposition to Disease Genetic research Genome-wide association studies Genome-Wide Association Study Genomes Genomics Growth factors Health aspects Humans Hyperactivity Identification and classification Immunoglobulin A Independent study Infant, Newborn Inflammation Inflammation - blood Inflammation - diagnosis Inflammation - immunology Interleukin 1 Interleukin 18 Interleukin 8 Male Medicine and Health Sciences Mental disorders Metabolites Monocyte chemoattractant protein 1 Monocytes Novels Polymorphism, Single Nucleotide Proteins Quantitative Trait Loci Regulation Replication S100 Calcium Binding Protein beta Subunit - blood S100 Calcium Binding Protein beta Subunit - genetics S100 Calcium Binding Protein beta Subunit - immunology S100b protein Schizophrenia
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