Effect of aerobic exercise on amyloid accumulation in preclinical Alzheimer's: A 1-year randomized controlled trial

Our goal was to investigate the role of physical exercise to protect brain health as we age, including the potential to mitigate Alzheimer's-related pathology. We assessed the effect of 52 weeks of a supervised aerobic exercise program on amyloid accumulation, cognitive performance, and brain v...

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Veröffentlicht in:	PloS one 2021-01, Vol.16 (1), p.e0244893
Hauptverfasser:	Vidoni, Eric D, Morris, Jill K, Watts, Amber, Perry, Mark, Clutton, Jon, Van Sciver, Angela, Kamat, Ashwini S, Mahnken, Jonathan, Hunt, Suzanne L, Townley, Ryan, Honea, Robyn, Shaw, Ashley R, Johnson, David K, Vacek, James, Burns, Jeffrey M
Format:	Artikel
Sprache:	eng
Schlagworte:	Aerobic exercises Aerobics Aged Alzheimer Disease - diagnostic imaging Alzheimer Disease - metabolism Alzheimer Disease - pathology Alzheimer Disease - physiopathology Alzheimer's disease Amyloid Amyloid - metabolism Amyloid beta-protein Animal cognition Biology and Life Sciences Brain - diagnostic imaging Brain - metabolism Brain - physiopathology Brain research Cervical cancer Cervical carcinoma Cervix Cognitive ability Computer programs Control Data analysis Dementia Development and progression Disease prevention Drafting software Editing Exercise Female Funding Health aspects Health care facilities Humans Hypertension Insulin Magnetic Resonance Imaging Male Medical treatment Medicine and Health Sciences Memory Methodology Neurodegeneration Neurodegenerative diseases Neurology Older people Pathophysiology People and Places Physical activity Physical fitness Physical training Physiological aspects Population studies Positron emission Positron emission tomography Prevention Prostate cancer Prostate carcinoma Psychology Radiology Research and Analysis Methods Reviews Skin cancer Software Tomography
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