Neuromarkers and neurological outcome in out-of-hospital cardiac arrest patients treated with therapeutic hypothermia-experience from the HAnnover COoling REgistry (HACORE)

Neuron-specific enolase (NSE) and S-100b have been used to assess neurological damage following out-of-hospital cardiac arrest (OHCA). Cut-offs were derived from small normothermic cohorts. Whether similar cut-offs apply to patients treated with hypothermia remained undetermined. We investigated 251...

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Veröffentlicht in:	PloS one 2021-01, Vol.16 (1), p.e0245210-e0245210
Hauptverfasser:	Akin, Muharrem, Garcheva, Vera, Sieweke, Jan-Thorben, Adel, John, Flierl, Ulrike, Bauersachs, Johann, Schäfer, Andreas
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biology and Life Sciences Biomarkers Biomarkers - blood Cardiac arrest Cardiology Care and treatment Clinical decision making Cooling Damage assessment Decision making Disease-Free Survival Emergency medical care Ethics Female Follow-Up Studies Heart Humans Hypothermia Hypothermia, Induced Intensive care Lactic acid Male Medical schools Medicine and Health Sciences Middle Aged Mortality Nervous system diseases Nervous System Diseases - blood Nervous System Diseases - mortality Out-of-Hospital Cardiac Arrest - blood Out-of-Hospital Cardiac Arrest - mortality Out-of-Hospital Cardiac Arrest - therapy Patient outcomes Patients Phosphopyruvate hydratase Phosphopyruvate Hydratase - blood Physical Sciences Prospective Studies Registries Regression analysis Rehabilitation Research and Analysis Methods Risk factors S100 Calcium Binding Protein beta Subunit - blood S100b protein Sepsis Survival Survival Rate Thresholds
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