Prognostic roles of diabetes mellitus and hypertension in advanced hepatocellular carcinoma treated with sorafenib

It remains limited whether diabetes mellitus (DM) and hypertension (HTN) affect the prognosis of advanced hepatocellular carcinoma (HCC) treated with sorafenib. Our study attempted to elucidate the roles of DM/HTN and the effects of diabetes medications among advanced HCC patients receiving sorafeni...

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Veröffentlicht in:	PloS one 2020-12, Vol.15 (12), p.e0244293-e0244293
Hauptverfasser:	Hsieh, Ming-Han, Kao, Tzu-Yu, Hsieh, Ting-Hui, Kao, Chun-Chi, Peng, Cheng-Yuan, Lai, Hsueh-Chou, Chuang, Po-Heng, Kao, Jung-Ta
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Antineoplastic Agents - therapeutic use Biology and life sciences Carcinoma, Hepatocellular - complications Carcinoma, Hepatocellular - drug therapy Carcinoma, Hepatocellular - physiopathology Cohort Studies Comorbidity Diabetes Diabetes Complications - physiopathology Diabetes mellitus Diabetes Mellitus - drug therapy Diabetes Mellitus - physiopathology Drug therapy Female Gastroenterology Growth factors Hepatocellular carcinoma Hepatology Hepatoma Hospitals Humans Hypertension Hypertension - complications Hypertension - physiopathology Inhibitor drugs Insulin Internal medicine Liver cancer Liver Neoplasms - complications Liver Neoplasms - physiopathology Male Medical prognosis Medicine Medicine and Health Sciences Metastasis Metformin Metformin - therapeutic use Middle Aged Patients Physical Sciences Prognosis Protamine sulfate Research and Analysis Methods Retrospective Studies Sorafenib - therapeutic use Survival Survival analysis Taiwan - epidemiology Targeted cancer therapy Tumors
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