Manufacturing of convalescent plasma of COVID-19 patients: Aspects of quality

The ongoing coronavirus disease 2019 (COVID-19) pandemic emerged in December 2019. Convalescent plasma represents a promising COVID-19 treatment. Here, we report on the manufacturing of a plasma-based product containing antibodies specific to SARS-CoV-2 obtained from recently recovered COVID-19 pati...

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Veröffentlicht in:	PloS one 2020-12, Vol.15 (12), p.e0243967
Hauptverfasser:	Hähnel, Viola, Peterhoff, David, Bäuerlein, Veronika, Brosig, Andreas-Michael, Pamler, Irene, Johnson, Christian, Bica, Adelina, Totir, Monica, Ossner, Thomas, Stemmer, Barbara, Toelge, Martina, Schütz, Anja, Niller, Hans-Helmut, Schmidt, Barbara, Wagner, Ralf, Gessner, André, Burkhard, Ralph, Offner, Robert
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Antibodies Antibodies, Viral - blood Antibodies, Viral - immunology Automation Binding Biology and Life Sciences Blood Clinical trials Coronaviruses COVID-19 COVID-19 - blood COVID-19 - epidemiology COVID-19 - immunology COVID-19 - therapy COVID-19 - virology COVID-19 Serotherapy Cytokines Endothelium Enzyme-Linked Immunosorbent Assay Enzymes Female Hospitals Humans Hygiene Immunization, Passive Immunoglobulin G Immunoglobulin G - blood Immunoglobulin G - immunology Immunoglobulin M - blood Immunoglobulin M - immunology Interleukin 8 Laboratories Male Medicine Medicine and Health Sciences Middle Aged Neutralization Tests Pandemics Patients Peripheral blood Plasma Plasma - immunology Plasma - virology Plasmapheresis Plasmapheresis - methods Polymerase chain reaction Proteins Research and Analysis Methods SARS-CoV-2 - immunology Severe acute respiratory syndrome Severe acute respiratory syndrome coronavirus 2 Supervision Tissue Donors Viral diseases Young Adult
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