Exploring the potential effect of paricalcitol on markers of inflammation in de novo renal transplant recipients

Following a successful renal transplantation circulating markers of inflammation may remain elevated, and systemic inflammation is associated with worse clinical outcome in renal transplant recipients (RTRs). Vitamin D-receptor (VDR) activation is postulated to modulate inflammation and endothelial...

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Veröffentlicht in:	PloS one 2020-12, Vol.15 (12), p.e0243759
Hauptverfasser:	Pihlstrøm, Hege Kampen, Ueland, Thor, Michelsen, Annika E, Aukrust, Pål, Gatti, Franscesca, Hammarström, Clara, Kasprzycka, Monika, Wang, Junbai, Haraldsen, Guttorm, Mjøen, Geir, Dahle, Dag Olav, Midtvedt, Karsten, Eide, Ivar Anders, Hartmann, Anders, Holdaas, Hallvard
Format:	Artikel
Sprache:	eng
Schlagworte:	Basale medisinske, odontologiske og veterinærmedisinske fag: 710 Basic medical, dental and veterinary science disciplines: 710 Biology and Life Sciences Biomarkers Biomarkers - blood Biomedical materials Biopsy Calciferol Calcification Causes of Cell activation Chronic illnesses Clinical medicine Complications Cytokines Diabetes Drug therapy Ergocalciferols - pharmacology Female Fibrosis Gene expression Gene Expression Regulation - drug effects Hospitals Humans Immune response Inflammation Inflammation - blood Inflammation - etiology Inflammation - immunology Internal medicine Kidney transplantation Kidney Transplantation - adverse effects Kidneys Laboratories Leukocytes Leukocytes - cytology Leukocytes - drug effects Male Medical disciplines: 700 Medicine Medicine and Health Sciences Medisinske Fag: 700 Methods Middle Aged Nephrology Osteoprotegerin Paricalcitol Pathology Patients Physical sciences Postoperative care Surgery Tissues Transplantation Transplants & implants Tumor necrosis factor-TNF VDP Vitamin D Vitamin D receptors
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