Meta-analysis of diagnostic accuracy of nucleic acid amplification tests for abdominal tuberculosis: A protocol

Abdominal tuberculosis is a severe extrapulmonary tuberculosis, which can lead to serious complications. Early diagnosis and treatment are very important for the prognosis and the diagnosis of abdominal tuberculosis is still difficult. This study aims to evaluate the diagnostic accuracy of nucleic a...

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Veröffentlicht in:PloS one 2020-12, Vol.15 (12), p.e0243765
Hauptverfasser: Shen, Yanqin, Fang, Likui, Ye, Bo, Yu, Guocan
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Fang, Likui
Ye, Bo
Yu, Guocan
description Abdominal tuberculosis is a severe extrapulmonary tuberculosis, which can lead to serious complications. Early diagnosis and treatment are very important for the prognosis and the diagnosis of abdominal tuberculosis is still difficult. This study aims to evaluate the diagnostic accuracy of nucleic acid amplification tests (NAATs) for abdominal tuberculosis using meta-analysis method. We will search PubMed, the Cochrane Library, Embase, China National Knowledge Infrastructure, and the Wanfang database for studies evaluating the diagnostic accuracy of NAATs for abdominal tuberculosis until May 2020. We will include a systematic review and meta-analysis that evaluated the accuracy of NAATs for abdominal tuberculosis. Any types of study design with full text will be sought and included. The risk of bias will be assessed using the Quality Assessment of Diagnostic Accuracy Studies tool. Stata version 15.0 with the midas command packages will be used to carry out meta-analyses. The results will provide clinical evidence for diagnostic accuracy of NAATs for abdominal tuberculosis, and this systematic review and meta-analysis will be submitted to a peer-reviewed journal for publication. This overview will provide evidence of NAATs for diagnosis of abdominal tuberculosis. INPLASY202060030.
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Early diagnosis and treatment are very important for the prognosis and the diagnosis of abdominal tuberculosis is still difficult. This study aims to evaluate the diagnostic accuracy of nucleic acid amplification tests (NAATs) for abdominal tuberculosis using meta-analysis method. We will search PubMed, the Cochrane Library, Embase, China National Knowledge Infrastructure, and the Wanfang database for studies evaluating the diagnostic accuracy of NAATs for abdominal tuberculosis until May 2020. We will include a systematic review and meta-analysis that evaluated the accuracy of NAATs for abdominal tuberculosis. Any types of study design with full text will be sought and included. The risk of bias will be assessed using the Quality Assessment of Diagnostic Accuracy Studies tool. Stata version 15.0 with the midas command packages will be used to carry out meta-analyses. 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subjects Abdomen
Abdomen - microbiology
Accuracy
Acids
Amplification
Biology and Life Sciences
Complications
Databases, Factual
Diagnosis
Diagnostic software
Diagnostic systems
Diagnostic tests
DNA, Bacterial - analysis
DNA, Bacterial - metabolism
DNA, Bacterial - standards
Evaluation
Health aspects
Hospitals
Humans
Inflammatory bowel disease
Libraries
Medical diagnosis
Medical prognosis
Medical research
Medical tests
Medicine
Medicine and Health Sciences
Meta-analysis
Meta-Analysis as Topic
Mycobacterium tuberculosis - genetics
Mycobacterium tuberculosis - isolation & purification
Nucleic Acid Amplification Techniques - methods
Nucleic acids
Peritonitis
Physical Sciences
Polymerase chain reaction
Quality assessment
Quality control
Quality standards
Reference Standards
Registered Report Protocol
Registration
Research and Analysis Methods
Researchers
Reviews
Systematic review
Systematic Reviews as Topic
Tuberculosis
Tuberculosis - diagnosis
Tuberculosis - microbiology
title Meta-analysis of diagnostic accuracy of nucleic acid amplification tests for abdominal tuberculosis: A protocol
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