B cells were related to HBsAg seroconversion in inactive HBsAg carriers following peginterferon therapy

Our recent study showed high rate of HBsAg seroconversion achieved in inactive HBsAg carriers (IHCs) treated with peginterferon (PEG-IFN). To better understand the immune-mediated component to the HBsAg seroconversion, we investigated the role of B cells in this study. A total of 44 IHCs were given...

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Veröffentlicht in:	PloS one 2020-12, Vol.15 (12), p.e0242559-e0242559
Hauptverfasser:	Cao, Zhenhuan, Meng, Sha, Zheng, Yanhong, Wang, Junli, Wang, Rui, Chen, Xinyue
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome Adult Age AIDS Antigens B cells B-Lymphocytes - immunology Biology and Life Sciences Carrier State - immunology Carriers Case-Control Studies Deoxyribonucleic acid DNA Dosage and administration Female Flow cytometry Hepatitis B surface antigen Hepatitis B Surface Antigens - blood Hospitals Humans Interferon Interferons - therapeutic use Liver diseases Lymphocytes B Male Medicine and Health Sciences Monoclonal antibodies Peginterferon alfa-2a Physiological aspects Plasma Plasma Cells - immunology Polyethylene Glycols - therapeutic use Research and Analysis Methods Seroconversion
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