UCP3 reciprocally controls CD4+ Th17 and Treg cell differentiation

Uncoupling proteins (UCPs) are members of the mitochondrial anion carrier superfamily that can mediate the transfer of protons into the mitochondrial matrix from the intermembrane space. We have previously reported UCP3 expression in thymocytes, mitochondria of total splenocytes and splenic lymphocy...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2020-11, Vol.15 (11), p.e0239713-e0239713
Hauptverfasser:	O'Connor, Emma B, Muñoz-Wolf, Natalia, Leon, Gemma, Lavelle, Ed C, Mills, Kingston H G, Walsh, Patrick T, Porter, Richard K
Format:	Artikel
Sprache:	eng
Schlagworte:	Ablation Animals Antigens Antigens, CD - metabolism Antigens, Differentiation, T-Lymphocyte - metabolism Autoimmune diseases Biochemistry Biology and Life Sciences CD25 antigen CD28 antigen CD4 antigen CD4 lymphocytes CD69 antigen Cell activation Cell differentiation Cell Differentiation - immunology Cell Proliferation - genetics Clinical medicine Cytokines Differentiation (biology) Ecstasy Foxp3 protein Gene expression Genetic aspects Health aspects Helper cells Immunization Immunology Interleukin 2 Interleukin-17 - metabolism Interleukin-2 - metabolism Interleukin-2 Receptor alpha Subunit - metabolism Laboratory animals Lectins, C-Type - metabolism Lymphocyte Activation - genetics Lymphocyte Activation - immunology Lymphocytes Lymphocytes T Medical treatment Medicine Medicine and Health Sciences Mice Mice, Inbred C57BL Mice, Knockout Mitochondria mRNA Musculoskeletal system Physiological aspects Proteins Protons Research and Analysis Methods Spleen Splenocytes Suppressor cells T cell receptors T-cell receptor T-Lymphocytes, Regulatory - cytology T-Lymphocytes, Regulatory - immunology Th17 Cells - cytology Th17 Cells - immunology Thymocytes Thymus gland Transcription factors Transport proteins Uncoupling Protein 3 - genetics Uncoupling Protein 3 - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!