Distal organ inflammation and injury after resuscitative endovascular balloon occlusion of the aorta in a porcine model of severe hemorrhagic shock

Resuscitative Endovascular Balloon Occlusion of Aorta (REBOA) has emerged as a potential life-saving maneuver for the management of non-compressible torso hemorrhage in trauma patients. Complete REBOA (cREBOA) is inherently associated with the burden of ischemia reperfusion injury (IRI) and organ dy...

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Veröffentlicht in:	PloS one 2020-11, Vol.15 (11), p.e0242450-e0242450
Hauptverfasser:	Li, Yansong, Dubick, Michael A, Yang, Zhangsheng, Barr, Johnny L, Gremmer, Brandon J, Lucas, Michael L, Necsoiu, Corina, Jordan, Bryan S, Batchinsky, Andriy I, Cancio, Leopoldo C
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdominal injuries Acidosis Anesthesia Animal protection Animal welfare Animals Aorta Aorta - physiopathology Balloon Occlusion - adverse effects Balloon Occlusion - methods Biology and Life Sciences Blood Pressure Blood Pressure Determination Blood Transfusion Blood volume Cardiovascular system Care and treatment Carotid arteries Catheters Coagulation Complications and side effects Compressibility Coronary vessels Creatinine Critical care Development and progression Endovascular Procedures - adverse effects Endovascular Procedures - methods Glutathione Heart rate Hemodynamics Hemorrhage Hemorrhagic shock Hyperkalemia IL-1β Inflammation Injuries Interleukin 6 Ischemia Jejunum Kidneys Laboratory animals Leukopenia Liver Liver - physiopathology Livestock Male Medicine and Health Sciences Metabolic acidosis Models, Animal Multiple organ failure Neutropenia Occlusion Organs Ostomy Perfusion Reperfusion Reperfusion Injury - physiopathology Resuscitation Resuscitation - methods Shock, Hemorrhagic - metabolism Shock, Hemorrhagic - physiopathology Side effects Swine Torso Torso - physiopathology Transfusion Trauma Tumor necrosis factor-α Vascular surgery Veins & arteries
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