Development of a multiplex microsphere immunoassay for the detection of antibodies against highly pathogenic viruses in human and animal serum samples

Surveillance of highly pathogenic viruses circulating in both human and animal populations is crucial to unveil endemic infections and potential zoonotic reservoirs. Monitoring the burden of disease by serological assay could be used as an early warning system for imminent outbreaks as an increased...

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Veröffentlicht in:	PLoS neglected tropical diseases 2020-10, Vol.14 (10), p.e0008699-e0008699
Hauptverfasser:	Surtees, Rebecca, Stern, Daniel, Ahrens, Katharina, Kromarek, Nicole, Lander, Angelika, Kreher, Petra, Weiss, Sabrina, Hewson, Roger, Punch, Emma K, Barr, John N, Witkowski, Peter T, Couacy-Hymann, Emmanuel, Marzi, Andrea, Dorner, Brigitte G, Kurth, Andreas
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal population Animal populations Animals Antibodies Antibodies, Viral - blood Antigens Binding Biology and life sciences Cellular biology Chiroptera Coccidioidomycosis Crimean hemorrhagic fever Defence mechanisms Detection Diagnosis Disease Early warning systems Ebola virus ELISA Enzyme-linked immunosorbent assay Epidemics Filoviridae Funding Hantavirus Health aspects Health surveillance High-throughput screening (Biochemical assaying) Human populations Humans Immune response Immune system Immunity Immunoassay Immunoassay - methods Immunoassays Immunoglobulin G Infections Inoculation Laboratories Livestock Medicine and Health Sciences Methods Microspheres Monitoring Multiplexing Nosocomial infections Nucleocapsid Proteins - immunology Nucleocapsids Nucleoproteins Optimization Orthohantavirus Outbreaks Pathogens Populations Primates Proteins Public health Research and Analysis Methods Rift Valley fever Samples Serology Serum Statistical analysis Statistical methods Stern, Daniel Tropical diseases Vector-borne diseases Viral antibodies Viral diseases Virology Virus diseases Virus Diseases - diagnosis Virus Diseases - veterinary Virus Diseases - virology Virus-like particles Viruses Wildlife Zoonoses
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