Vitamin A supplementation boosts control of antibiotic-resistant Salmonella infection in malnourished mice

Disseminated disease from non-typhoidal Salmonella enterica strains results in >20% mortality globally. Barriers to effective treatment include emerging multidrug resistance, antibiotic treatment failure, and risk factors such as malnutrition and related micronutrient deficiencies. Individuals in...

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Veröffentlicht in:	PLoS neglected tropical diseases 2020-10, Vol.14 (10), p.e0008737-e0008737
Hauptverfasser:	Stull-Lane, Annica R, Lokken-Toyli, Kristen L, Diaz-Ochoa, Vladimir E, Walker, Gregory T, Cevallos, Stephanie A, Winter, Andromeda L N, Muñoz, Ariel Del Hoyo, Yang, Guiyan G, Velazquez, Eric M, Wu, Chun-Yi, Tsolis, Renée M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal protection Animal welfare Animals Anti-Bacterial Agents - therapeutic use Antibiotic resistance Antibiotics Bacteremia Bacteremia - drug therapy Bacteremia - microbiology Biology and Life Sciences Body weight gain Body weight loss Care and treatment Context Control Diet Dietary Supplements Disease Models, Animal Disseminated infection Drug resistance Drug Resistance, Multiple, Bacterial Experiments Failure Female Females Health services Immunology Infections Laboratory animals Liver Male Males Malnutrition Malnutrition - physiopathology Medical research Medicine and Health Sciences Mice Mice, Inbred C57BL Microbiological strains Mortality Multidrug resistance Nutrient deficiency Patients Physical sciences Research and Analysis Methods Retinene Risk analysis Risk factors Salmonella Salmonella Infections - drug therapy Salmonella Infections - microbiology Salmonella typhimurium - drug effects Salmonellosis Sex Factors Strains Survival Survival Rate Therapy Tropical diseases Veterinary medicine Vitamin A Vitamin A - administration & dosage Vitamin A deficiency Vitamin A Deficiency - physiopathology Vitamins Weight gain Weight loss
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