Drug effects on metabolic profiles of Schistosoma mansoni adult male parasites detected by 1H-NMR spectroscopy

Schistosomiasis is one of the most devastating neglected tropical parasitic diseases caused by trematodes of the genus Schistosoma. Praziquantel (PZQ) is today the only drug used in humans and animals for the treatment of schistosomiasis but unfortunately it is poorly effective on larval and juvenil...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PLoS neglected tropical diseases 2020-10, Vol.14 (10), p.e0008767
Hauptverfasser:	Guidi, Alessandra, Petrella, Greta, Fustaino, Valentina, Saccoccia, Fulvio, Lentini, Sara, Gimmelli, Roberto, Di Pietro, Giulia, Bresciani, Alberto, Cicero, Daniel Oscar, Ruberti, Giovina
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Analytical methods Animals Anthelmintics - administration & dosage Biochemistry Biology Biology and Life Sciences Carnitine Chromatography Computer and Information Sciences Councils Developmental stages Drug Monitoring - methods Drugs Experiments Fatty acids Female Funding Humans Lipid metabolism Lipids Magnetic resonance spectroscopy Male Males Medicine and Health Sciences Metabolic pathways Metabolism Metabolites Metabolome - drug effects Metabolomics Mice, Inbred ICR NMR NMR spectroscopy Nuclear magnetic resonance Parasites Parasitic diseases Parasitoses Perhexiline - administration & dosage Perhexiline - analogs & derivatives Praziquantel Praziquantel - administration & dosage Profiles Proton Magnetic Resonance Spectroscopy - methods Schistosoma mansoni Schistosoma mansoni - drug effects Schistosoma mansoni - growth & development Schistosoma mansoni - metabolism Schistosomiasis Schistosomiasis mansoni - drug therapy Schistosomiasis mansoni - parasitology Specificity Spectroscopy Therapeutic targets Tropical climate Tropical diseases Worms
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!