Development of an immuno-wall device for the rapid and sensitive detection of EGFR mutations in tumor tissues resected from lung cancer patients

Detecting molecular targets in specimens from patients with lung cancer is essential for targeted therapy. Recently, we developed a highly sensitive, rapid-detection device (an immuno-wall device) that utilizes photoreactive polyvinyl alcohol immobilized with antibodies against a target protein via...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2020-11, Vol.15 (11), p.e0241422-e0241422
Hauptverfasser:	Yogo, Naoyuki, Hase, Tetsunari, Kasama, Toshihiro, Nishiyama, Keine, Ozawa, Naoya, Hatta, Takahiro, Shibata, Hirofumi, Sato, Mitsuo, Komeda, Kazuki, Kawabe, Nozomi, Matsuoka, Kohei, Chen-Yoshikawa, Toyofumi Fengshi, Kaji, Noritada, Tokeshi, Manabu, Baba, Yoshinobu, Hasegawa, Yoshinori
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Assaying Biology and Life Sciences Biotin Calibration Cancer Care and treatment Cell Line, Tumor Cloning Deletion Diagnosis Diagnostic software Diagnostic systems DNA Mutational Analysis - instrumentation Engineering schools Epidermal growth factor Epidermal growth factor receptors ErbB Receptors - genetics ErbB Receptors - immunology Fluorescence Gene deletion Gene mutations Genotype Genotyping Growth factors Humans Immunoassay Kinases Laboratories Lung cancer Lung cancer, Non-small cell Lung diseases Lung Neoplasms - genetics Medicine Medicine and Health Sciences Molecular diagnostic techniques Mutation Mutation - genetics Non-small cell lung carcinoma Oncology, Experimental Performance evaluation Polyvinyl alcohol Protein-tyrosine kinase Research and Analysis Methods Small cell lung carcinoma Streptavidin Substitutes Target detection Thoracic surgery Tyrosine University graduates
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!