AKH-FOXO pathway regulates starvation-induced sleep loss through remodeling of the small ventral lateral neuron dorsal projections

Starvation caused by adverse feeding stresses or food shortages has been reported to result in sleep loss in animals. However, how the starvation signal interacts with the central nervous system is still unknown. Here, the adipokinetic hormone (AKH)-Fork head Box-O (FOXO) pathway is shown to respond...

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Veröffentlicht in:	PLoS genetics 2020-10, Vol.16 (10), p.e1009181-e1009181
Hauptverfasser:	He, Qiankun, Du, Juan, Wei, Liya, Zhao, Zhangwu
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animals Animals, Genetically Modified Behavior Biology and Life Sciences Causes of Cellular signal transduction Central nervous system Circadian rhythm Circadian Rhythm - genetics Control Dietary restrictions Drosophila Drosophila melanogaster - genetics Drosophila Proteins - genetics Energy Entomology Food Food Deprivation - physiology Forkhead protein Forkhead Transcription Factors - genetics Gene expression Genetic aspects Hyperactivity Insect Hormones - genetics Insects Kinases Light Medicine and Health Sciences Metabolism MicroRNAs Neurons Neurons - metabolism Oligopeptides - genetics Physical Sciences Physiological aspects Pyrrolidonecarboxylic Acid - analogs & derivatives Research and Analysis Methods Signal Transduction - genetics Sleep Sleep - genetics Sleep - physiology Sleep deprivation Social Sciences Software Starvation Starvation - genetics Starvation - metabolism Synapses
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