Urine metabolomics of rats with chronic atrophic gastritis

To use liquid chromatography-mass spectrometry (LC-MS) to identify endogenous differential metabolites in the urine of rats with chronic atrophic gastritis (CAG). Methylnitronitrosoguanidine (MNNG) was used to produce a CAG model in Wistar rats, and HE staining was used to determine the pathological...

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Veröffentlicht in:	PloS one 2020-11, Vol.15 (11), p.e0236203-e0236203
Hauptverfasser:	Zu, Guo-Xiu, Sun, Qian-Qian, Chen, Jian, Liu, Xi-Jian, Sun, Ke-Yun, Zhang, Liang-Kun, Li, Ling, Han, Tao, Huang, Hai-Liang
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Animals Biology and Life Sciences Biomarkers - urine Chinese medicine Chromatography Disease Models, Animal Ethics Experiments Gastritis Gastritis, Atrophic - pathology Gastritis, Atrophic - urine Glutamic acid Glutamine Histidine Identification and classification Liquid chromatography Male Mass spectrometry Mass spectroscopy Medicine and Health Sciences Metabolic Networks and Pathways Metabolic pathways Metabolism Metabolites Metabolomics Metabolomics - methods Methods Pathogenesis Physical Sciences Physiological aspects Rats Rats, Wistar Research and Analysis Methods Scientific imaging Statistical analysis Statistical methods Trinucleotide repeats Urine
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