CX3CL1 and IL-15 Promote CD8 T cell chemoattraction in HIV and in atherosclerosis

Atherosclerotic cardiovascular disease (ASCVD) remains an important cause of morbidity in the general population and risk for ASCVD is increased approximately 2-fold in persons living with HIV infection (PLWH). This risk is linked to elevated CD8 T cell counts that are abundant in atherosclerotic pl...

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Veröffentlicht in:	PLoS pathogens 2020-09, Vol.16 (9), p.e1008885-e1008885
Hauptverfasser:	Panigrahi, Soumya, Chen, Bonnie, Fang, Mike, Potashnikova, Daria, Komissarov, Alexey A, Lebedeva, Anna, Michaelson, Gillian M, Wyrick, Jonathan M, Morris, Stephen R, Sieg, Scott F, Paiardini, Mirko, Villinger, Francois J, Harth, Karem, Kashyap, Vikram S, Cameron, Mark J, Cameron, Cheryl M, Vasilieva, Elena, Margolis, Leonid, Younes, Souheil-Antoine, Funderburg, Nicholas T, Zidar, David A, Lederman, Michael M, Freeman, Michael L
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome Aged Aging AIDS Animals Aorta Arteriosclerosis Atherosclerosis Atherosclerosis - metabolism Biology and Life Sciences Blood vessels Cardiovascular disease Cardiovascular diseases CD8 antigen CD8 lymphocytes CD8-Positive T-Lymphocytes - metabolism Cell activation Cell adhesion & migration Chemokine CX3CL1 - metabolism Chemokines CX3CR1 protein Cytokines Dentistry Development and progression Endothelial cells Endothelial Cells - metabolism Endothelium Funding Genetic aspects Geriatrics Health aspects Health risks Health sciences HIV HIV infections HIV Infections - metabolism Hospitals Human immunodeficiency virus Humans Immunological memory Infections Infectious diseases Interleukin 15 Interleukin-15 - metabolism Interleukins Laboratories Lymphocytes Lymphocytes T Macaca mulatta - metabolism Medicine Medicine and Health Sciences Memory cells Morbidity Muscles Older people Pathogenesis Phenotypes Plaques Population Receptors, Chemokine - metabolism Recruitment Smooth muscle Software Stokes, Louis Supervision
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