Discovery of repurposing drug candidates for the treatment of diseases caused by pathogenic free-living amoebae

Diseases caused by pathogenic free-living amoebae include primary amoebic meningoencephalitis (Naegleria fowleri), granulomatous amoebic encephalitis (Acanthamoeba spp.), Acanthamoeba keratitis, and Balamuthia amoebic encephalitis (Balamuthia mandrillaris). Each of these are difficult to treat and h...

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Veröffentlicht in:	PLoS neglected tropical diseases 2020-09, Vol.14 (9), p.e0008353-e0008353
Hauptverfasser:	Rice, Christopher A, Colon, Beatrice L, Chen, Emily, Hull, Mitchell V, Kyle, Dennis E
Format:	Artikel
Sprache:	eng
Schlagworte:	Acanthamoeba Acanthamoeba castellanii Acriflavine Amoeba Amoebas Antibiotics Balamuthia mandrillaris Biology and Life Sciences Brain research Cellular biology Chemotherapy Cysts Diseases Drug development Drug discovery Drug therapy Drugs Encephalitis Health aspects Infections Infectious diseases Inhibitors Keratitis Medical treatment Medicine and Health Sciences Meningitis Meningoencephalitis Morbidity Mortality Naegleria fowleri Nose Parasitic diseases Pathogens Patients Pharmacological research Primary amebic meningoencephalitis Rare diseases Research and Analysis Methods Skin Transplants & implants Tropical diseases
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