Wide range of G6PD activities found among ethnic groups of the Chittagong Hill Tracts, Bangladesh

The proportion of Plasmodium vivax malaria among all malarias is increasing worldwide. Treatment with 8-aminoquinolines remain the only radical cure. However, 8-aminoquinolines can cause severe hemolysis in glucose-6-phosphate dehydrogenase (G6PD) deficient patients. The population of the multi-ethn...

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Veröffentlicht in:	PLoS neglected tropical diseases 2020-09, Vol.14 (9), p.e0008697
Hauptverfasser:	Ley, Benedikt, Kibria, Mohammad Golam, Khan, Wasif Ali, Auburn, Sarah, Phru, Ching Swe, Jahan, Nusrat, Johora, Fatema Tuj, Thriemer, Kamala, Ami, Jenifar Quaiyum, Hossain, Mohammad Sharif, Price, Ric N, Koepfli, Cristian, Alam, Mohammad Shafiul
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aminoquinolines Aminoquinolines - adverse effects Aminoquinolines - therapeutic use Bangladesh - epidemiology Biology and Life Sciences Clinical medicine Complications and side effects Consent Control Darwin, Charles (1809-1882) Diagnostic systems Diagnostic Tests, Routine DNA Drug therapy Ethics Ethnicity Ethnicity - genetics Female Genotypes Genotyping Glucose 6 phosphate dehydrogenase Glucose-6-phosphate dehydrogenase deficiency Glucosephosphate dehydrogenase Glucosephosphate Dehydrogenase - genetics Glucosephosphate Dehydrogenase - metabolism Glucosephosphate Dehydrogenase Deficiency - complications Glucosephosphate Dehydrogenase Deficiency - diagnosis Glucosephosphate Dehydrogenase Deficiency - epidemiology Glucosephosphate Dehydrogenase Deficiency - genetics Haemolysis Hemolysis Households Human diseases Humans Infectious diseases Laboratories Local population Malaria Malaria, Vivax - complications Malaria, Vivax - drug therapy Malaria, Vivax - epidemiology Male Medical research Medicine Medicine and Health Sciences Microscopy Middle Aged Minority & ethnic groups Nucleotide sequence PCR People and Places Phosphates Polymerase Chain Reaction Population Prevalence Quinolines Research and Analysis Methods Risk factors Spectrophotometry Statistics Testing Tropical diseases Vector-borne diseases Young Adult
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