Protective effects of citrulline supplementation in ulcerative colitis rats

It has been reported that supplementing certain amino acids has therapeutic effects on ulcerative colitis (UC). We intend to explore whether citrulline (Cit) supplementation has protective effects on UC. Fifteen male Wistar rats were divided into normal control group (NC group), UC group and UC+Cit...

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Veröffentlicht in:	PloS one 2020-10, Vol.15 (10), p.e0240883-e0240883
Hauptverfasser:	Cai, Bin, Zhou, Min-Hong, Huang, Hua-Li, Zhou, A-Cheng, Chu, Zheng-da, Huang, Xiao-Dong, Li, Chun-Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Animal models Animals Antigens, CD - metabolism Antigens, Differentiation, Myelomonocytic - metabolism Bioavailability Biology and Life Sciences Blood Body Weight Body weight loss Care and treatment Chinese medicine Citrulline Citrulline - therapeutic use Colitis, Ulcerative - drug therapy Colitis, Ulcerative - pathology Colon Colon - metabolism Colon - pathology Decomposition Dietary Supplements Disease Models, Animal Enzyme-linked immunosorbent assay Ethanol Immunohistochemistry Infiltration Inflammatory bowel disease Interleukin 6 Interleukin-17 - metabolism Interleukin-6 - metabolism Male Medical research Medicine and Health Sciences Metabolism Monocyte chemoattractant protein 1 Monocytes Monocytes - cytology Monocytes - immunology Monocytes - metabolism Peripheral blood Phosphorylation Protective Agents - therapeutic use Proteins Rats Rats, Wistar Rodents Staining Stat3 protein STAT3 Transcription Factor - metabolism Statistical analysis Statistical methods Supplements Surgery Testing Tissues Ulcerative colitis Weight loss
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