Aromatherapy improves cognitive dysfunction in senescence-accelerated mouse prone 8 by reducing the level of amyloid beta and tau phosphorylation

Alzheimer's disease (AD) is a progressive neurodegenerative disease and is known to be the most common cause of dementia. We previously described the benefits of aromatherapy on the cognitive function of patients with AD utilizing various aromatic essential oils; however, its mechanism of actio...

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Veröffentlicht in:	PloS one 2020-10, Vol.15 (10), p.e0240378-e0240378
Hauptverfasser:	Okuda, Michiaki, Fujita, Yuki, Takada-Takatori, Yuki, Sugimoto, Hachiro, Urakami, Katsuya
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - psychology Alzheimer Disease - therapy Alzheimer's disease Amyloid beta-Peptides - metabolism Amyloid beta-protein Animal cognition Animals Aromatherapy Aromatherapy - methods Biology and Life Sciences Brain Brain - drug effects Brain - metabolism Brain-derived neurotrophic factor Brain-Derived Neurotrophic Factor - metabolism Care and treatment Citrus - chemistry Citrus fruits Clinical trials Cognitive ability Cognitive Dysfunction - therapy Dementia Dementia disorders Diagnosis Disease Models, Animal Down-Regulation Essential oils Humans Male Maze Learning Measurement Medicine and Health Sciences Memory Mice Nervous system Neurodegenerative diseases Oils & fats Oils, Volatile - administration & dosage Oils, Volatile - pharmacology Oranges Pharmaceutical sciences Phosphorylation Plant Oils - administration & dosage Plant Oils - pharmacology Prevention Research and Analysis Methods Senescence Tau protein Tau proteins tau Proteins - metabolism Testing Treatment Outcome
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