MiR103a-3p and miR107 are related to adaptive coping in a cluster of fibromyalgia patients

MicroRNA (miRNA) mainly inhibit post-transcriptional gene expression of specific targets and may modulate disease severity. We aimed to identify miRNA signatures distinguishing patient clusters with fibromyalgia syndrome (FMS). We previously determined four FMS patient clusters labelled "malada...

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Veröffentlicht in:	PloS one 2020-09, Vol.15 (9), p.e0239286-e0239286
Hauptverfasser:	Braun, Alexandra, Evdokimov, Dimitar, Frank, Johanna, Sommer, Claudia, Üçeyler, Nurcan
Format:	Artikel
Sprache:	eng
Schlagworte:	Abuse Adaptation, Psychological Biology and life sciences Blood Care and treatment Chromosome 3 Clusters Coping Coping (Psychology) Female Fibromyalgia Fibromyalgia - genetics Fibromyalgia - psychology Gene expression Genetic aspects Health aspects Humans Inflammation Kinases Leukocytes Male Medicine and Health Sciences MicroRNA MicroRNAs MicroRNAs - genetics MicroRNAs - metabolism Middle Aged miRNA Neurology Pain Pathophysiology Post-transcription Protein kinase Protein-serine/threonine kinase Psychological aspects Questionnaires Research and Analysis Methods Resilience Resilience, Psychological Ribonucleic acid RNA Statistical analysis Stress Sucrose Sugar Target recognition Threonine TLR4 protein Toll-like receptors Trauma Tumor necrosis factor-TNF Up-Regulation Variance analysis
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