Information transmission from NFkB signaling dynamics to gene expression

The dynamic signal encoding paradigm suggests that information flows from the extracellular environment into specific signaling patterns (encoding) that are then read by downstream effectors to control cellular behavior. Previous work empirically quantified the information content of dynamic signali...

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Veröffentlicht in:	PLoS computational biology 2020-08, Vol.16 (8), p.e1008011-e1008011
Hauptverfasser:	Maity, Alok, Wollman, Roy
Format:	Artikel
Sprache:	eng
Schlagworte:	Accuracy Biology and Life Sciences Cell interactions Cellular signal transduction Computer and Information Sciences Computer simulation Gene expression Genetic aspects Information flow Information processing Kinases Ligands Mathematical models Model accuracy NF-κB protein Noise Noise reduction Physical Sciences Random variables Research and Analysis Methods Signal encoding Signaling Transcription factors
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