Evolution-guided mutagenesis of the cytoplasmic incompatibility proteins: Identifying CifA's complex functional repertoire and new essential regions in CifB

Wolbachia are the world's most common, maternally-inherited, arthropod endosymbionts. Their worldwide distribution is due, in part, to a selfish drive system termed cytoplasmic incompatibility (CI) that confers a relative fitness advantage to females that transmit Wolbachia to their offspring....

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Veröffentlicht in:	PLoS pathogens 2020-08, Vol.16 (8), p.e1008794
Hauptverfasser:	Shropshire, J Dylan, Kalra, Mahip, Bordenstein, Seth R
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Animals Animals, Genetically Modified - microbiology Animals, Genetically Modified - physiology Bacteria Bacterial Proteins - genetics Bacterial Proteins - metabolism Biological Evolution Biology and Life Sciences Catalase Cellular proteins Cytoplasm Cytoplasm - metabolism Cytoplasm - microbiology Cytoplasmic incompatibility Domains Drosophila melanogaster - microbiology Drosophila melanogaster - physiology Embryos Endosymbionts Evolution Female Females Genetic aspects Gram-Negative Bacterial Infections - metabolism Gram-Negative Bacterial Infections - microbiology Gram-Negative Bacterial Infections - pathology Immunology Incompatibility Infections Male Males Medicine and Health Sciences Mutagenesis Mutation Natural history Nuclease Offspring Ovaries Peptidase Phages Phylogenetics Physiological aspects Proteins Research and Analysis Methods Residues Sperm Spermatogenesis Testes Wolbachia Wolbachia - physiology
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