Off-pump versus on-pump coronary artery surgery in octogenarians (from the KROK Registry)
According to the medical literature, both on-pump and off-pump coronary artery surgery is safe and effective in octogenarians. The aim of our study was to examine the epidemiology, in-hospital outcomes and long-term follow-up results in octogenarians undergoing off-pump and on-pump coronary artery s...
Gespeichert in:
| Veröffentlicht in: | PloS one 2020-09, Vol.15 (9), p.e0238880-e0238880 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | e0238880 |
|---|---|
| container_issue | 9 |
| container_start_page | e0238880 |
| container_title | PloS one |
| container_volume | 15 |
| creator | Knapik, Piotr Hirnle, Grzegorz Kowalczuk-Wieteska, Anetta O.Zembala, Michal Pawlak, Szymon Hrapkowicz, Tomasz Przybylowski, Piotr Nadziakiewicz, Pawel Ciesla, Daniel Perek, Bartlomiej Kapelak, Boguslaw Cisowski, Marek Rogowski, Jan Pietrzyk, Edward Tobota, Zdzislaw Zembala, Marian |
| description | According to the medical literature, both on-pump and off-pump coronary artery surgery is safe and effective in octogenarians. The aim of our study was to examine the epidemiology, in-hospital outcomes and long-term follow-up results in octogenarians undergoing off-pump and on-pump coronary artery surgery utilizing nationwide registry data. All octogenarians ([greater than or equal to] 80 years) enrolled in the Polish National Registry of Cardiac Surgical Procedures (KROK Registry), who underwent isolated coronary surgery between January 2006 and September 2017 were identified. Preoperative data, perioperative complications, hospital mortality and long-term mortality were analyzed. Unadjusted and propensity-matched comparisons were performed between octogenarians undergoing off-pump and on-pump coronary artery bypass surgery. Octogenarians accounted for 4.1% of the total population undergoing coronary artery surgery in Poland during the analyzed period (n = 152,631) and this percentage is increasing. Among 6,006 analyzed patients, 2,744 (45.7%) were operated on-pump and 3,262 (54.3%) were operated off-pump. Propensity-matched analysis revealed that patients operated on-pump were more often reoperated due to postoperative bleeding and their in-hospital mortality was higher (6.6% vs 4.5%, p = 0.006 and 8.7% vs 5.8%, p = 0.001, respectively). Long-term all-cause mortality was lower among patients operated off-pump (p = 0.013). On the basis of our findings we suggest that off pump technique should be considered as perfectly acceptable in octogenarians. |
| doi_str_mv | 10.1371/journal.pone.0238880 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_plos_</sourceid><recordid>TN_cdi_plos_journals_2441546866</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A635043082</galeid><doaj_id>oai_doaj_org_article_2f28eae8a9674810bf15e494bddba8f2</doaj_id><sourcerecordid>A635043082</sourcerecordid><originalsourceid>FETCH-LOGICAL-c669t-542aaaf3f012f5bb3be2ddfc045565e089ea9b62af7c481f5ae834c7151f44b33</originalsourceid><addsrcrecordid>eNqNk1uL1DAUx4so7rr6DQQLguw-zJhrm74Iy-Jl2IWB8QI-hTQ96WRomzFJF_fbm3GqbGUfJA8nl1_-J_9DTpa9xGiJaYnf7tzoB9Ut926AJSJUCIEeZae4omRREEQf35ufZM9C2CHEqSiKp9kJJRWmlFen2fe1MYv92O_zW_BhDLkbjkvtvBuUv8uVj5BCGH17iHbInY6uhXRo1RDyc-Ndn8ct5Neb9XW-gdaG6O8unmdPjOoCvJjiWfb1w_svV58WN-uPq6vLm4UuiiouOCNKKUMNwsTwuqY1kKYxGjHOCw5IVKCquiDKlJoJbLgCQZkuMceGsZrSs-zVUXffuSCnqgRJGMOcFclvIlZHonFqJ_fe9smXdMrK3xvOtzKZtLoDSQwRkDKoqihTNlQbzIFVrG6aWglDkta7KdtY99BoGKJX3Ux0fjLYrWzdrUxypCrLJHA-CXj3Y4QQZW-Dhq5TA7jx-O4CU4FEQl__gz7sbqJalQzYwbiUVx9E5WVBOWIUicO7lw9QaTTQW52-kLFpf3bhYnYhMRF-xlaNIcjV583_s-tvc_bNPXYLqovb4LoxWjeEOciOoPYuBA_mb5ExkocO-FMNeegAOXUA_QW9L_cR</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2441546866</pqid></control><display><type>article</type><title>Off-pump versus on-pump coronary artery surgery in octogenarians (from the KROK Registry)</title><source>DOAJ Directory of Open Access Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Public Library of Science (PLoS)</source><source>PubMed Central</source><source>Free Full-Text Journals in Chemistry</source><creator>Knapik, Piotr ; Hirnle, Grzegorz ; Kowalczuk-Wieteska, Anetta ; O.Zembala, Michal ; Pawlak, Szymon ; Hrapkowicz, Tomasz ; Przybylowski, Piotr ; Nadziakiewicz, Pawel ; Ciesla, Daniel ; Perek, Bartlomiej ; Kapelak, Boguslaw ; Cisowski, Marek ; Rogowski, Jan ; Pietrzyk, Edward ; Tobota, Zdzislaw ; Zembala, Marian</creator><contributor>Kowalewski, Mariusz</contributor><creatorcontrib>Knapik, Piotr ; Hirnle, Grzegorz ; Kowalczuk-Wieteska, Anetta ; O.Zembala, Michal ; Pawlak, Szymon ; Hrapkowicz, Tomasz ; Przybylowski, Piotr ; Nadziakiewicz, Pawel ; Ciesla, Daniel ; Perek, Bartlomiej ; Kapelak, Boguslaw ; Cisowski, Marek ; Rogowski, Jan ; Pietrzyk, Edward ; Tobota, Zdzislaw ; Zembala, Marian ; on behalf of KROK Investigators ; Kowalewski, Mariusz</creatorcontrib><description>According to the medical literature, both on-pump and off-pump coronary artery surgery is safe and effective in octogenarians. The aim of our study was to examine the epidemiology, in-hospital outcomes and long-term follow-up results in octogenarians undergoing off-pump and on-pump coronary artery surgery utilizing nationwide registry data. All octogenarians ([greater than or equal to] 80 years) enrolled in the Polish National Registry of Cardiac Surgical Procedures (KROK Registry), who underwent isolated coronary surgery between January 2006 and September 2017 were identified. Preoperative data, perioperative complications, hospital mortality and long-term mortality were analyzed. Unadjusted and propensity-matched comparisons were performed between octogenarians undergoing off-pump and on-pump coronary artery bypass surgery. Octogenarians accounted for 4.1% of the total population undergoing coronary artery surgery in Poland during the analyzed period (n = 152,631) and this percentage is increasing. Among 6,006 analyzed patients, 2,744 (45.7%) were operated on-pump and 3,262 (54.3%) were operated off-pump. Propensity-matched analysis revealed that patients operated on-pump were more often reoperated due to postoperative bleeding and their in-hospital mortality was higher (6.6% vs 4.5%, p = 0.006 and 8.7% vs 5.8%, p = 0.001, respectively). Long-term all-cause mortality was lower among patients operated off-pump (p = 0.013). On the basis of our findings we suggest that off pump technique should be considered as perfectly acceptable in octogenarians.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0238880</identifier><identifier>PMID: 32913359</identifier><language>eng</language><publisher>San Francisco: Public Library of Science</publisher><subject>Anesthesiology ; Biology and Life Sciences ; Bleeding ; Cardiovascular disease ; Care and treatment ; Complications ; Coronary artery ; Coronary artery bypass ; Coronary vessels ; Emergency medical care ; Epidemiology ; Heart surgery ; Hospitals ; Ischemia ; Medicine and Health Sciences ; Methods ; Mortality ; Octogenarians ; Patient outcomes ; Patients ; Population ; Postoperative period ; Surgeons ; Surgery ; Variables ; Vascular surgery ; Ventilators</subject><ispartof>PloS one, 2020-09, Vol.15 (9), p.e0238880-e0238880</ispartof><rights>COPYRIGHT 2020 Public Library of Science</rights><rights>2020 Knapik et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2020 Knapik et al 2020 Knapik et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c669t-542aaaf3f012f5bb3be2ddfc045565e089ea9b62af7c481f5ae834c7151f44b33</citedby><cites>FETCH-LOGICAL-c669t-542aaaf3f012f5bb3be2ddfc045565e089ea9b62af7c481f5ae834c7151f44b33</cites><orcidid>0000-0002-1058-1502 ; 0000-0003-0664-0925 ; 0000-0002-7162-4481 ; 0000-0003-1813-2354</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482977/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482977/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,2095,2914,23846,27903,27904,53769,53771,79346,79347</link.rule.ids></links><search><contributor>Kowalewski, Mariusz</contributor><creatorcontrib>Knapik, Piotr</creatorcontrib><creatorcontrib>Hirnle, Grzegorz</creatorcontrib><creatorcontrib>Kowalczuk-Wieteska, Anetta</creatorcontrib><creatorcontrib>O.Zembala, Michal</creatorcontrib><creatorcontrib>Pawlak, Szymon</creatorcontrib><creatorcontrib>Hrapkowicz, Tomasz</creatorcontrib><creatorcontrib>Przybylowski, Piotr</creatorcontrib><creatorcontrib>Nadziakiewicz, Pawel</creatorcontrib><creatorcontrib>Ciesla, Daniel</creatorcontrib><creatorcontrib>Perek, Bartlomiej</creatorcontrib><creatorcontrib>Kapelak, Boguslaw</creatorcontrib><creatorcontrib>Cisowski, Marek</creatorcontrib><creatorcontrib>Rogowski, Jan</creatorcontrib><creatorcontrib>Pietrzyk, Edward</creatorcontrib><creatorcontrib>Tobota, Zdzislaw</creatorcontrib><creatorcontrib>Zembala, Marian</creatorcontrib><creatorcontrib>on behalf of KROK Investigators</creatorcontrib><title>Off-pump versus on-pump coronary artery surgery in octogenarians (from the KROK Registry)</title><title>PloS one</title><description>According to the medical literature, both on-pump and off-pump coronary artery surgery is safe and effective in octogenarians. The aim of our study was to examine the epidemiology, in-hospital outcomes and long-term follow-up results in octogenarians undergoing off-pump and on-pump coronary artery surgery utilizing nationwide registry data. All octogenarians ([greater than or equal to] 80 years) enrolled in the Polish National Registry of Cardiac Surgical Procedures (KROK Registry), who underwent isolated coronary surgery between January 2006 and September 2017 were identified. Preoperative data, perioperative complications, hospital mortality and long-term mortality were analyzed. Unadjusted and propensity-matched comparisons were performed between octogenarians undergoing off-pump and on-pump coronary artery bypass surgery. Octogenarians accounted for 4.1% of the total population undergoing coronary artery surgery in Poland during the analyzed period (n = 152,631) and this percentage is increasing. Among 6,006 analyzed patients, 2,744 (45.7%) were operated on-pump and 3,262 (54.3%) were operated off-pump. Propensity-matched analysis revealed that patients operated on-pump were more often reoperated due to postoperative bleeding and their in-hospital mortality was higher (6.6% vs 4.5%, p = 0.006 and 8.7% vs 5.8%, p = 0.001, respectively). Long-term all-cause mortality was lower among patients operated off-pump (p = 0.013). On the basis of our findings we suggest that off pump technique should be considered as perfectly acceptable in octogenarians.</description><subject>Anesthesiology</subject><subject>Biology and Life Sciences</subject><subject>Bleeding</subject><subject>Cardiovascular disease</subject><subject>Care and treatment</subject><subject>Complications</subject><subject>Coronary artery</subject><subject>Coronary artery bypass</subject><subject>Coronary vessels</subject><subject>Emergency medical care</subject><subject>Epidemiology</subject><subject>Heart surgery</subject><subject>Hospitals</subject><subject>Ischemia</subject><subject>Medicine and Health Sciences</subject><subject>Methods</subject><subject>Mortality</subject><subject>Octogenarians</subject><subject>Patient outcomes</subject><subject>Patients</subject><subject>Population</subject><subject>Postoperative period</subject><subject>Surgeons</subject><subject>Surgery</subject><subject>Variables</subject><subject>Vascular surgery</subject><subject>Ventilators</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>DOA</sourceid><recordid>eNqNk1uL1DAUx4so7rr6DQQLguw-zJhrm74Iy-Jl2IWB8QI-hTQ96WRomzFJF_fbm3GqbGUfJA8nl1_-J_9DTpa9xGiJaYnf7tzoB9Ut926AJSJUCIEeZae4omRREEQf35ufZM9C2CHEqSiKp9kJJRWmlFen2fe1MYv92O_zW_BhDLkbjkvtvBuUv8uVj5BCGH17iHbInY6uhXRo1RDyc-Ndn8ct5Neb9XW-gdaG6O8unmdPjOoCvJjiWfb1w_svV58WN-uPq6vLm4UuiiouOCNKKUMNwsTwuqY1kKYxGjHOCw5IVKCquiDKlJoJbLgCQZkuMceGsZrSs-zVUXffuSCnqgRJGMOcFclvIlZHonFqJ_fe9smXdMrK3xvOtzKZtLoDSQwRkDKoqihTNlQbzIFVrG6aWglDkta7KdtY99BoGKJX3Ux0fjLYrWzdrUxypCrLJHA-CXj3Y4QQZW-Dhq5TA7jx-O4CU4FEQl__gz7sbqJalQzYwbiUVx9E5WVBOWIUicO7lw9QaTTQW52-kLFpf3bhYnYhMRF-xlaNIcjV583_s-tvc_bNPXYLqovb4LoxWjeEOciOoPYuBA_mb5ExkocO-FMNeegAOXUA_QW9L_cR</recordid><startdate>20200910</startdate><enddate>20200910</enddate><creator>Knapik, Piotr</creator><creator>Hirnle, Grzegorz</creator><creator>Kowalczuk-Wieteska, Anetta</creator><creator>O.Zembala, Michal</creator><creator>Pawlak, Szymon</creator><creator>Hrapkowicz, Tomasz</creator><creator>Przybylowski, Piotr</creator><creator>Nadziakiewicz, Pawel</creator><creator>Ciesla, Daniel</creator><creator>Perek, Bartlomiej</creator><creator>Kapelak, Boguslaw</creator><creator>Cisowski, Marek</creator><creator>Rogowski, Jan</creator><creator>Pietrzyk, Edward</creator><creator>Tobota, Zdzislaw</creator><creator>Zembala, Marian</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0002-1058-1502</orcidid><orcidid>https://orcid.org/0000-0003-0664-0925</orcidid><orcidid>https://orcid.org/0000-0002-7162-4481</orcidid><orcidid>https://orcid.org/0000-0003-1813-2354</orcidid></search><sort><creationdate>20200910</creationdate><title>Off-pump versus on-pump coronary artery surgery in octogenarians (from the KROK Registry)</title><author>Knapik, Piotr ; Hirnle, Grzegorz ; Kowalczuk-Wieteska, Anetta ; O.Zembala, Michal ; Pawlak, Szymon ; Hrapkowicz, Tomasz ; Przybylowski, Piotr ; Nadziakiewicz, Pawel ; Ciesla, Daniel ; Perek, Bartlomiej ; Kapelak, Boguslaw ; Cisowski, Marek ; Rogowski, Jan ; Pietrzyk, Edward ; Tobota, Zdzislaw ; Zembala, Marian</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c669t-542aaaf3f012f5bb3be2ddfc045565e089ea9b62af7c481f5ae834c7151f44b33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Anesthesiology</topic><topic>Biology and Life Sciences</topic><topic>Bleeding</topic><topic>Cardiovascular disease</topic><topic>Care and treatment</topic><topic>Complications</topic><topic>Coronary artery</topic><topic>Coronary artery bypass</topic><topic>Coronary vessels</topic><topic>Emergency medical care</topic><topic>Epidemiology</topic><topic>Heart surgery</topic><topic>Hospitals</topic><topic>Ischemia</topic><topic>Medicine and Health Sciences</topic><topic>Methods</topic><topic>Mortality</topic><topic>Octogenarians</topic><topic>Patient outcomes</topic><topic>Patients</topic><topic>Population</topic><topic>Postoperative period</topic><topic>Surgeons</topic><topic>Surgery</topic><topic>Variables</topic><topic>Vascular surgery</topic><topic>Ventilators</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Knapik, Piotr</creatorcontrib><creatorcontrib>Hirnle, Grzegorz</creatorcontrib><creatorcontrib>Kowalczuk-Wieteska, Anetta</creatorcontrib><creatorcontrib>O.Zembala, Michal</creatorcontrib><creatorcontrib>Pawlak, Szymon</creatorcontrib><creatorcontrib>Hrapkowicz, Tomasz</creatorcontrib><creatorcontrib>Przybylowski, Piotr</creatorcontrib><creatorcontrib>Nadziakiewicz, Pawel</creatorcontrib><creatorcontrib>Ciesla, Daniel</creatorcontrib><creatorcontrib>Perek, Bartlomiej</creatorcontrib><creatorcontrib>Kapelak, Boguslaw</creatorcontrib><creatorcontrib>Cisowski, Marek</creatorcontrib><creatorcontrib>Rogowski, Jan</creatorcontrib><creatorcontrib>Pietrzyk, Edward</creatorcontrib><creatorcontrib>Tobota, Zdzislaw</creatorcontrib><creatorcontrib>Zembala, Marian</creatorcontrib><creatorcontrib>on behalf of KROK Investigators</creatorcontrib><collection>CrossRef</collection><collection>Gale In Context: Opposing Viewpoints</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Meteorological & Geoastrophysical Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Materials Science Database</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Meteorological & Geoastrophysical Abstracts - Academic</collection><collection>ProQuest Engineering Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Agricultural Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Engineering Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>Materials Science Collection</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>Engineering Collection</collection><collection>Environmental Science Collection</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Knapik, Piotr</au><au>Hirnle, Grzegorz</au><au>Kowalczuk-Wieteska, Anetta</au><au>O.Zembala, Michal</au><au>Pawlak, Szymon</au><au>Hrapkowicz, Tomasz</au><au>Przybylowski, Piotr</au><au>Nadziakiewicz, Pawel</au><au>Ciesla, Daniel</au><au>Perek, Bartlomiej</au><au>Kapelak, Boguslaw</au><au>Cisowski, Marek</au><au>Rogowski, Jan</au><au>Pietrzyk, Edward</au><au>Tobota, Zdzislaw</au><au>Zembala, Marian</au><au>Kowalewski, Mariusz</au><aucorp>on behalf of KROK Investigators</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Off-pump versus on-pump coronary artery surgery in octogenarians (from the KROK Registry)</atitle><jtitle>PloS one</jtitle><date>2020-09-10</date><risdate>2020</risdate><volume>15</volume><issue>9</issue><spage>e0238880</spage><epage>e0238880</epage><pages>e0238880-e0238880</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>According to the medical literature, both on-pump and off-pump coronary artery surgery is safe and effective in octogenarians. The aim of our study was to examine the epidemiology, in-hospital outcomes and long-term follow-up results in octogenarians undergoing off-pump and on-pump coronary artery surgery utilizing nationwide registry data. All octogenarians ([greater than or equal to] 80 years) enrolled in the Polish National Registry of Cardiac Surgical Procedures (KROK Registry), who underwent isolated coronary surgery between January 2006 and September 2017 were identified. Preoperative data, perioperative complications, hospital mortality and long-term mortality were analyzed. Unadjusted and propensity-matched comparisons were performed between octogenarians undergoing off-pump and on-pump coronary artery bypass surgery. Octogenarians accounted for 4.1% of the total population undergoing coronary artery surgery in Poland during the analyzed period (n = 152,631) and this percentage is increasing. Among 6,006 analyzed patients, 2,744 (45.7%) were operated on-pump and 3,262 (54.3%) were operated off-pump. Propensity-matched analysis revealed that patients operated on-pump were more often reoperated due to postoperative bleeding and their in-hospital mortality was higher (6.6% vs 4.5%, p = 0.006 and 8.7% vs 5.8%, p = 0.001, respectively). Long-term all-cause mortality was lower among patients operated off-pump (p = 0.013). On the basis of our findings we suggest that off pump technique should be considered as perfectly acceptable in octogenarians.</abstract><cop>San Francisco</cop><pub>Public Library of Science</pub><pmid>32913359</pmid><doi>10.1371/journal.pone.0238880</doi><tpages>e0238880</tpages><orcidid>https://orcid.org/0000-0002-1058-1502</orcidid><orcidid>https://orcid.org/0000-0003-0664-0925</orcidid><orcidid>https://orcid.org/0000-0002-7162-4481</orcidid><orcidid>https://orcid.org/0000-0003-1813-2354</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1932-6203 |
| ispartof | PloS one, 2020-09, Vol.15 (9), p.e0238880-e0238880 |
| issn | 1932-6203 1932-6203 |
| language | eng |
| recordid | cdi_plos_journals_2441546866 |
| source | DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Public Library of Science (PLoS); PubMed Central; Free Full-Text Journals in Chemistry |
| subjects | Anesthesiology Biology and Life Sciences Bleeding Cardiovascular disease Care and treatment Complications Coronary artery Coronary artery bypass Coronary vessels Emergency medical care Epidemiology Heart surgery Hospitals Ischemia Medicine and Health Sciences Methods Mortality Octogenarians Patient outcomes Patients Population Postoperative period Surgeons Surgery Variables Vascular surgery Ventilators |
| title | Off-pump versus on-pump coronary artery surgery in octogenarians (from the KROK Registry) |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-25T21%3A19%3A40IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Off-pump%20versus%20on-pump%20coronary%20artery%20surgery%20in%20octogenarians%20(from%20the%20KROK%20Registry)&rft.jtitle=PloS%20one&rft.au=Knapik,%20Piotr&rft.aucorp=on%20behalf%20of%20KROK%20Investigators&rft.date=2020-09-10&rft.volume=15&rft.issue=9&rft.spage=e0238880&rft.epage=e0238880&rft.pages=e0238880-e0238880&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0238880&rft_dat=%3Cgale_plos_%3EA635043082%3C/gale_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2441546866&rft_id=info:pmid/32913359&rft_galeid=A635043082&rft_doaj_id=oai_doaj_org_article_2f28eae8a9674810bf15e494bddba8f2&rfr_iscdi=true |