Difference in pyruvic acid metabolism between neonatal and adult mouse lungs exposed to hyperoxia

Objective Neonatal lungs are more tolerant to hyperoxic injury than are adult lungs. This study investigated differences in the response to hyperoxic exposure between neonatal and adult mouse lungs using metabolomics analysis with capillary electrophoresis time-of-flight mass spectrometry (CE- TOFMS...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2020-09, Vol.15 (9), p.e0238604-e0238604
Hauptverfasser:	Tanaka, Kosuke, Watanabe, Takaaki, Ozawa, Junichi, Ito, Masato, Nagano, Nobuhiko, Arai, Yukio, Miyake, Fuyu, Matsumura, Shun, Kobayashi, Shingo, Itakura, Ryuta, Namba, Fumihiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Biology and Life Sciences Capillary electrophoresis Dehydrogenases Disease Electrophoresis Enzymatic activity Enzyme activity Enzymes Epithelium Exposure Gene expression Gluconeogenesis Glycolysis Hyperoxia Immunohistochemistry Kinases Laboratory animals Lactic acid Localization Lungs Mass spectrometry Mass spectroscopy Medicine and Health Sciences Metabolism Metabolites Metabolomics Neonates Newborn babies Pediatrics Phosphoenolpyruvic acid Physical Sciences Polymerase chain reaction Proteins Pyruvic acid Research and Analysis Methods Reverse transcription Rodents Western blotting
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!