MITF and TFEB cross-regulation in melanoma cells

The MITF, TFEB, TFE3 and TFEC (MiT-TFE) proteins belong to the basic helix-loop-helix family of leucine zipper transcription factors. MITF is crucial for melanocyte development and differentiation, and has been termed a lineage-specific oncogene in melanoma. The three related proteins MITF, TFEB and...

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Veröffentlicht in:	PloS one 2020-09, Vol.15 (9), p.e0238546-e0238546
Hauptverfasser:	Ballesteros-Álvarez, Josué, Dilshat, Ramile, Fock, Valerie, Möller, Katrín, Karl, Ludwig, Larue, Lionel, Ögmundsdóttir, Margrét Helga, Steingrímsson, Eiríkur
Format:	Artikel
Sprache:	eng
Schlagworte:	Autophagy Binding sites Biochemistry Biology and life sciences Deoxyribonucleic acid DNA Gene expression Helix-loop-helix proteins Helix-loop-helix proteins (basic) Kinases Leucine Leucine zipper proteins Localization Lysosomes Medicine Melanoma Microphthalmia-associated transcription factor Molecular biology Mutation Phagosomes Proteins Research and Analysis Methods Signal transduction TOR protein Transcription factors Tumors
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