Racial differences in α4β7 expression on CD4+ T cells of HIV-negative men and women who inject drugs

We performed a cross-sectional study of HIV-uninfected men and women who inject drugs from the ALIVE cohort to examine if black men and women who inject drugs have higher levels of CD4+ T cells expressing the integrin heterodimer α4β7 compared to white men and women. Flow cytometry was used to exami...

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Veröffentlicht in:	PloS one 2020-08, Vol.15 (8), p.e0238234
Hauptverfasser:	Martin, Alyssa R, Sivro, Aida, Packman, Zoe R, Patel, Eshan U, Goes, Livia R, McKinnon, Lyle R, Astemborski, Jacquie, Kirk, Gregory D, Mehta, Shruti H, Cicala, Claudia, Arthos, James, Redd, Andrew D, Quinn, Thomas C
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome Adult AIDS Antibodies Baltimore Biology and Life Sciences Black or African American CCR5 protein CCR6 protein CD4 antigen CD4-Positive T-Lymphocytes - immunology Cohort Studies Cross-Sectional Studies Drug use Drugs Epidemiology Female Flow Cytometry Health risks Herpes viruses HIV HIV Seronegativity - immunology Human immunodeficiency virus Humans Infections Infectious diseases Integrins - blood Lymphocytes Lymphocytes T Male Medicine Medicine and Health Sciences Men Middle Aged Population Public health Race Racial differences Regression analysis Research and Analysis Methods Sexually transmitted diseases STD Substance Abuse, Intravenous - blood Substance Abuse, Intravenous - immunology White People Women Womens health
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