Tocilizumab and steroid treatment in patients with COVID-19 pneumonia

Coronavirus disease 2019 (COVID-19) can lead to respiratory failure due to severe immune response. Treatment targeting this immune response might be beneficial but there is limited evidence on its efficacy. The aim of this study was to determine if early treatment of patients with COVID-19 pneumonia...

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Veröffentlicht in:	PloS one 2020-08, Vol.15 (8), p.e0237831-e0237831
Hauptverfasser:	Mikulska, Malgorzata, Nicolini, Laura Ambra, Signori, Alessio, Di Biagio, Antonio, Sepulcri, Chiara, Russo, Chiara, Dettori, Silvia, Berruti, Marco, Sormani, Maria Pia, Giacobbe, Daniele Roberto, Vena, Antonio, De Maria, Andrea, Dentone, Chiara, Taramasso, Lucia, Mirabella, Michele, Magnasco, Laura, Mora, Sara, Delfino, Emanuele, Toscanini, Federica, Balletto, Elisa, Alessandrini, Anna Ida, Baldi, Federico, Briano, Federica, Camera, Marco, Dodi, Ferdinando, Ferrazin, Antonio, Labate, Laura, Mazzarello, Giovanni, Pincino, Rachele, Portunato, Federica, Tutino, Stefania, Barisione, Emanuela, Bruzzone, Bianca, Orsi, Andrea, Schenone, Eva, Rosseti, Nirmala, Sasso, Elisabetta, Da Rin, Giorgio, Pelosi, Paolo, Beltramini, Sabrina, Giacomini, Mauro, Icardi, Giancarlo, Gratarola, Angelo, Bassetti, Matteo
Format:	Artikel
Sprache:	eng
Schlagworte:	Bioengineering Biology and Life Sciences Coronaviruses COVID-19 Cytokines Drug therapy Failure Health sciences Hospitals Hydroxychloroquine Hygiene Immune response Immune system Immunosuppressive agents Infectious diseases Inflammation Informatics Intubation Medicine and Health Sciences Methylprednisolone Monoclonal antibodies Mortality Neurosciences Pandemics Patient outcomes Patients Pharmacy Physical Sciences Pneumonia Regression analysis Respiratory failure Ritonavir Robotics Severe acute respiratory syndrome coronavirus 2 Steroid hormones Steroids Supervision Survival Tocilizumab Ventilators Viral diseases
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