A retrospective study on nested PCR detection of syphilis treponemes in clinical samples: PCR detection contributes to the diagnosis of syphilis in patients with seronegative and serodiscrepant results

Syphilis, caused by Treponema pallidum ssp. pallidum (TPA), is a persisting global health problem. Although syphilis diagnostics relies mainly on serology, serological tests have some limitations, and it is recommended that the final diagnosis be supported by additional tests. The purpose of this st...

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Veröffentlicht in:	PloS one 2020-08, Vol.15 (8), p.e0237949-e0237949
Hauptverfasser:	Vrbová, Eliška, Mikalová, Lenka, Grillová, Linda, Pospíšilová, Petra, Strnadel, Radim, Dastychová, Eliška, Kojanová, Martina, Kreidlová, Miluše, Vaňousová, Daniela, Rob, Filip, Procházka, Přemysl, Krchňáková, Alena, Vašků, Vladimír, Woznicová, Vladana, Dvořáková Heroldová, Monika, Kuklová, Ivana, Zákoucká, Hana, Šmajs, David
Format:	Artikel
Sprache:	eng
Schlagworte:	Biology Biology and Life Sciences Deoxyribonucleic acid Dermatology Diagnosis DNA EDTA Global health Globus pallidus Hospitals Identification and classification Laboratories Medical diagnosis Medicine Medicine and Health Sciences Methods Molecular diagnostic techniques Polymerase chain reaction Public health Research and Analysis Methods Serological tests Serology Sexually transmitted diseases STD Syphilis Treponema Ulcers
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