Efficacy and safety of bempedoic acid for the treatment of hypercholesterolemia: A systematic review and meta-analysis

Bempedoic acid is a first-in-class lipid-lowering drug recommended by guidelines for the treatment of hypercholesterolemia. Our objective was to estimate its average effect on plasma lipids in humans and its safety profile. We carried out a systematic review and meta-analysis of phase II and III ran...

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Veröffentlicht in:	PLoS medicine 2020-07, Vol.17 (7), p.e1003121-e1003121
Hauptverfasser:	Cicero, Arrigo F. G, Fogacci, Federica, Hernandez, Adrian V, Banach, Maciej, Misra, Adya
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Anticholesteremic agents Apolipoprotein A Apolipoprotein B Apolipoproteins Bias Biology and Life Sciences Blood lipids C-reactive protein Cholesterol Creatine Creatine kinase Diabetes mellitus Drug therapy Enzymes Hypercholesterolemia Hypertension Infections Lipids Lipoproteins Liver Low density lipoproteins Medicine and Health Sciences Meta-analysis Online databases Pain Physical Sciences Research and Analysis Methods Safety Science Policy Studies Systematic review Uric acid
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