Extracellular Vesicle cystatin c is associated with unstable angina in troponin negative patients with acute chest pain

Despite the use of high-sensitive cardiac troponin there remains a group of high-sensitive cardiac troponin negative patients with unstable angina with a non-neglectable risk for future adverse cardiovascular events, emphasising the need for additional risk stratification. Plasma extracellular vesic...

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Veröffentlicht in:	PloS one 2020-08, Vol.15 (8), p.e0237036
Hauptverfasser:	Dekker, Mirthe, Waissi, Farahnaz, van Bennekom, Joelle, Silvis, Max J M, Timmerman, Nathalie, Schoneveld, Arjan H, Grobbee, Diederick E, de Winter, Robbert J, Mosterd, Arend, Timmers, Leo, de Kleijn, Dominique P V
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Coronary Syndrome - physiopathology Acute coronary syndromes Adult Aged Angina Angina pectoris Angina, Unstable - blood Angina, Unstable - metabolism Angina, Unstable - physiopathology Biology and Life Sciences Biomarkers Biomarkers - blood Calcium-binding protein Cardiology Cardiovascular diseases Case-Control Studies Chest Chest Pain - blood Chest Pain - metabolism Chest Pain - physiopathology Cohort Studies Creatine Kinase - blood Cystatin Cystatin C Cystatin C - analysis Cystatin C - blood Cystatin C - metabolism Diagnosis Electrocardiography Electrochemiluminescence Extracellular vesicles Extracellular Vesicles - metabolism Extracellular Vesicles - physiology Female Funding Health aspects Health risks Heart Heart attacks High density lipoprotein Humans Immunoassay Ischemia Lipids Lipoproteins (high density) Lipoproteins (low density) Low density lipoprotein Male Medicine and Health Sciences Membrane vesicles Middle Aged Myocardial Infarction - physiopathology Pain Pathophysiology Physiological aspects Plasma Proteins Retrospective Studies Risk Studies Troponin Troponin - blood Unstable angina Vascular surgery Vesicles
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