Immunodeficient mice are better for modeling the transfusion of human blood components than wild-type mice

Animal models are vital to the study of transfusion and development of new blood products. Post-transfusion recovery of human blood components can be studied in mice, however, there is a need to identify strains that can best tolerate xenogeneic transfusions, as well as to optimize such protocols. S...

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Veröffentlicht in:PloS one 2020-07, Vol.15 (7), p.e0237106-e0237106
Hauptverfasser: Blessinger, Sophia A, Tran, Johnson Q, Jackman, Rachael P, Gilfanova, Renata, Rittenhouse, Jacqueline, Gutierrez, Alan G, Heitman, John W, Hazegh, Kelsey, Kanias, Tamir, Muench, Marcus O
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