A chronic rejection model and potential biomarkers for vascularized composite allotransplantation

Chronic rejection remains the Achilles heel in vascularized composite allotransplantation. Animal models to specifically study chronic rejection in vascularized composite allotransplantation do not exist so far. However, there are established rat models to study chronic rejection in solid organ tran...

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Veröffentlicht in:	PloS one 2020-06, Vol.15 (6), p.e0235266-e0235266
Hauptverfasser:	Puscz, Flemming, Dadras, Mehran, Dermietzel, Alexander, Jacobsen, Frank, Lehnhardt, Marcus, Behr, Björn, Hirsch, Tobias, Kueckelhaus, Maximilian
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Antibodies Biology and Life Sciences Biomarkers CD4 antigen Cell proliferation Change detection Complications and side effects Cytokines Development and progression Fibrosis Graft rejection Hand surgery Histology Homografts Immunohistochemistry Immunosuppression Inflammation Laboratory animals Ligands Medicine and Health Sciences Muscles Physiological aspects Plastic surgery Reconstructive surgery Rejection Research and Analysis Methods Skin Transplantation Vascular grafts Veins & arteries
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