Mitotic activity index and CD25+ lymphocytes predict risk of stage progression in non-muscle invasive bladder cancer

In urothelial cell type non-muscle invasive urinary bladder carcinoma, TNM stage and WHO grade are widely used to classify patients into low and high-risk groups for prognostic and therapeutic decision-making. However, stage and grade reproducibility and prediction accuracy are wanting. This may lea...

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Veröffentlicht in:	PloS one 2020-06, Vol.15 (6), p.e0233676-e0233676
Hauptverfasser:	Lillesand, Melinda, Kvikstad, Vebjørn, Mangrud, Ok Målfrid, Gudlaugsson, Einar, van Diermen-Hidle, Bianca, Skaland, Ivar, Baak, Jan P. A, Janssen, Emiel A. M
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antigens Automation Bacillus Calmette-Guerin vaccine BCG Biology and Life Sciences Biopsy Bladder Bladder cancer Cancer Cancer cells Cancer patients Carcinoma CD25 antigen CD4 antigen CD8 antigen Cell proliferation Cloning Composition Cytotoxicity Decision making Development and progression EDTA Health aspects Immunotherapy Invasiveness Lymphocytes Medical diagnosis Medical prognosis Medicine and Health Sciences Metastasis Mitomycin Mitosis Multivariate analysis Muscles Pathology Physiological aspects Plasma cells Prognosis Recurrence (Disease) Research and Analysis Methods Risk Risk groups T cells Tumors Urinary bladder Urinary bladder carcinoma Urothelial cancer
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