Expression of high mobility group B1 and toll-like receptor-nuclear factor κB signaling pathway in chronic subdural hematomas

Chronic subdural hematoma (CSDH) is an angiogenic and inflammatory disease. Toll-like receptors (TLRs) transduce intracellular signals, resulting in the activation of nuclear factor κB (NF-κB), which leads to the production of inflammatory cytokines. High-mobility group box 1 (HMGB1) functions as a...

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Veröffentlicht in:PloS one 2020-06, Vol.15 (6), p.e0233643-e0233643
Hauptverfasser: Osuka, Koji, Watanabe, Yasuo, Usuda, Nobuteru, Iwami, Kenichiro, Miyachi, Shigeru, Takayasu, Masakazu
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Sprache:eng
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