Sequencing B cell receptors from ferrets (Mustela putorius furo)

The domestic ferret (Mustela putorius furo) provides a critical animal model to study human respiratory diseases. However immunological insights are restricted due to a lack of ferret-specific reagents and limited genetic information about ferret B and T cell receptors. Here, variable, diversity and...

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Veröffentlicht in:	PloS one 2020-05, Vol.15 (5), p.e0233794-e0233794
Hauptverfasser:	Wong, Julius, Tai, Celeste M, Hurt, Aeron C, Tan, Hyon-Xhi, Kent, Stephen J, Wheatley, Adam K
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Antibodies Antigens B cells Biology and Life Sciences Cell receptors Chains Cloning Domestic animals Expression vectors Ferrets Gene sequencing Genes Genomics Immunoglobulins Immunology Infections Influenza Interrogation Lymphocytes Lymphocytes B Lymphocytes T Mammals Medicine and Health Sciences Monoclonal antibodies Mustela putorius furo Pathogenesis Phylogenetics Physiological aspects Polymerase chain reaction Reagents Receptors Research and Analysis Methods Respiratory diseases Viral diseases
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