Preliminary study on Se-enriched Lentinula edodes mycelium as a proposal of new feed additive in selenium deficiency
The presence of selenium in European soil is low and this causes its deficiency in livestock and, in consequence, in humans. This study aimed to obtain Lentinula (L.) edodes mycelium with the maximum content of selenium. This species was used for experiment based on its documented medicinal properti...
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| creator | Muszyńska, Bożena Szacawa, Ewelina Bederska-Łojewska, Dorota Dudek, Katarzyna Pomierny, Bartosz Włodarczyk, Anna Kała, Katarzyna Lazur, Jan Suchocki, Piotr Budziszewska, Bogusława Bednarek, Dariusz Pieszka, Marek |
| description | The presence of selenium in European soil is low and this causes its deficiency in livestock and, in consequence, in humans. This study aimed to obtain Lentinula (L.) edodes mycelium with the maximum content of selenium. This species was used for experiment based on its documented medicinal properties. Calves were fed with selenium-enriched L. edodes mycelium, and serum selenium concentration, average daily weight gains and selected immune parameters were estimated. The selenium-enriched mushroom was found to be safe based on cytotoxicity tests (MTT and LDH tests) and for this reason it was used for further experiments. The mean quantity of selenium in the serum of calves fed with selenium-enriched L. edodes mycelium was significantly higher than that of control calves. Additionally, the calves fed with selenium-enriched L. edodes mycelium had higher body weight gains than those of control calves. White blood cell counts and subpopulations of lymphocytes in the experimental and control calves were within the reference range. The administration of L. edodes enriched with selenium had a beneficial effect on state of health of the calves. |
| doi_str_mv | 10.1371/journal.pone.0233456 |
| format | Article |
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This study aimed to obtain Lentinula (L.) edodes mycelium with the maximum content of selenium. This species was used for experiment based on its documented medicinal properties. Calves were fed with selenium-enriched L. edodes mycelium, and serum selenium concentration, average daily weight gains and selected immune parameters were estimated. The selenium-enriched mushroom was found to be safe based on cytotoxicity tests (MTT and LDH tests) and for this reason it was used for further experiments. The mean quantity of selenium in the serum of calves fed with selenium-enriched L. edodes mycelium was significantly higher than that of control calves. Additionally, the calves fed with selenium-enriched L. edodes mycelium had higher body weight gains than those of control calves. White blood cell counts and subpopulations of lymphocytes in the experimental and control calves were within the reference range. The administration of L. edodes enriched with selenium had a beneficial effect on state of health of the calves.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0233456</identifier><identifier>PMID: 32437465</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Animal feeding and feeds ; Biology and Life Sciences ; Biomass ; Body weight ; Body weight gain ; Calves ; Cancer ; Cattle ; Cattle feed ; Composition ; Cytotoxicity ; Edible mushrooms ; EDTA ; Enrichment ; Feed additives ; Feed science ; Feeds ; Food and nutrition ; Health aspects ; Immune system ; Leukocytes ; Livestock ; Lymphocytes ; Medical schools ; Medicine and Health Sciences ; Mushrooms ; Parameter estimation ; Pharmaceuticals ; Pharmacy ; Physical Sciences ; Product development ; Reason ; Research and analysis methods ; Selenium ; Selenium (Chemical element) ; Selenium (Nutrient) ; Sheep ; Subpopulations ; Toxicity ; Toxicology ; White blood cell count</subject><ispartof>PloS one, 2020-05, Vol.15 (5), p.e0233456</ispartof><rights>COPYRIGHT 2020 Public Library of Science</rights><rights>2020 Muszyńska et al. 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The administration of L. edodes enriched with selenium had a beneficial effect on state of health of the calves.</description><subject>Animal feeding and feeds</subject><subject>Biology and Life Sciences</subject><subject>Biomass</subject><subject>Body weight</subject><subject>Body weight gain</subject><subject>Calves</subject><subject>Cancer</subject><subject>Cattle</subject><subject>Cattle feed</subject><subject>Composition</subject><subject>Cytotoxicity</subject><subject>Edible mushrooms</subject><subject>EDTA</subject><subject>Enrichment</subject><subject>Feed additives</subject><subject>Feed science</subject><subject>Feeds</subject><subject>Food and nutrition</subject><subject>Health aspects</subject><subject>Immune system</subject><subject>Leukocytes</subject><subject>Livestock</subject><subject>Lymphocytes</subject><subject>Medical schools</subject><subject>Medicine and Health Sciences</subject><subject>Mushrooms</subject><subject>Parameter 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consequence, in humans. This study aimed to obtain Lentinula (L.) edodes mycelium with the maximum content of selenium. This species was used for experiment based on its documented medicinal properties. Calves were fed with selenium-enriched L. edodes mycelium, and serum selenium concentration, average daily weight gains and selected immune parameters were estimated. The selenium-enriched mushroom was found to be safe based on cytotoxicity tests (MTT and LDH tests) and for this reason it was used for further experiments. The mean quantity of selenium in the serum of calves fed with selenium-enriched L. edodes mycelium was significantly higher than that of control calves. Additionally, the calves fed with selenium-enriched L. edodes mycelium had higher body weight gains than those of control calves. White blood cell counts and subpopulations of lymphocytes in the experimental and control calves were within the reference range. The administration of L. edodes enriched with selenium had a beneficial effect on state of health of the calves.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>32437465</pmid><doi>10.1371/journal.pone.0233456</doi><tpages>e0233456</tpages><orcidid>https://orcid.org/0000-0003-1815-5724</orcidid><orcidid>https://orcid.org/0000-0002-5121-467X</orcidid><oa>free_for_read</oa></addata></record> |
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| ispartof | PloS one, 2020-05, Vol.15 (5), p.e0233456 |
| issn | 1932-6203 1932-6203 |
| language | eng |
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| source | DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Public Library of Science (PLoS); PubMed Central; Free Full-Text Journals in Chemistry |
| subjects | Animal feeding and feeds Biology and Life Sciences Biomass Body weight Body weight gain Calves Cancer Cattle Cattle feed Composition Cytotoxicity Edible mushrooms EDTA Enrichment Feed additives Feed science Feeds Food and nutrition Health aspects Immune system Leukocytes Livestock Lymphocytes Medical schools Medicine and Health Sciences Mushrooms Parameter estimation Pharmaceuticals Pharmacy Physical Sciences Product development Reason Research and analysis methods Selenium Selenium (Chemical element) Selenium (Nutrient) Sheep Subpopulations Toxicity Toxicology White blood cell count |
| title | Preliminary study on Se-enriched Lentinula edodes mycelium as a proposal of new feed additive in selenium deficiency |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-25T06%3A13%3A26IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Preliminary%20study%20on%20Se-enriched%20Lentinula%20edodes%20mycelium%20as%20a%20proposal%20of%20new%20feed%20additive%20in%20selenium%20deficiency&rft.jtitle=PloS%20one&rft.au=Muszy%C5%84ska,%20Bo%C5%BCena&rft.date=2020-05-21&rft.volume=15&rft.issue=5&rft.spage=e0233456&rft.pages=e0233456-&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0233456&rft_dat=%3Cgale_plos_%3EA624573600%3C/gale_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2405599521&rft_id=info:pmid/32437465&rft_galeid=A624573600&rft_doaj_id=oai_doaj_org_article_ec9db2f71986482b8f39e060afb27857&rfr_iscdi=true |