Oncogenic effects of RAB27B through exosome independent function in renal cell carcinoma including sunitinib-resistant

Exosomes are 40-100 nm nano-sized extracellular vesicles. They are released from many cell types and move into the extracellular space, thereby transferring their components to recipient cells. Exosomes are receiving increasing attention as novel structures participating in intracellular communicati...

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Veröffentlicht in:	PloS one 2020-05, Vol.15 (5), p.e0232545-e0232545
Hauptverfasser:	Tsuruda, Masafumi, Yoshino, Hirofumi, Okamura, Shunsuke, Kuroshima, Kazuki, Osako, Yoichi, Sakaguchi, Takashi, Sugita, Satoshi, Tatarano, Shuichi, Nakagawa, Masayuki, Enokida, Hideki
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticancer properties Antineoplastic agents Biology and Life Sciences Biotechnology Cancer Cancer metastasis Cancer research Carcinoma Care and treatment Cell migration Cell proliferation Cellular signal transduction Development and progression Drug resistance Endothelial growth factors Exosomes Extracellular vesicles Genetic aspects Health aspects Immunoglobulins Inhibitor drugs Intracellular signalling Invasiveness Kidney cancer Kinases MAP kinase Medicine and Health Sciences Membrane proteins Metastases Metastasis MicroRNAs Nucleotide sequence Organelles Patient outcomes Proteins Recurrence (Disease) Renal cell carcinoma Renal function Research and Analysis Methods Ribonucleic acid RNA Sunitinib Targeted cancer therapy Therapeutic applications Tumors Urology Vascular endothelial growth factor
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