Helminth infection modulates systemic pro-inflammatory cytokines and chemokines implicated in type 2 diabetes mellitus pathogenesis

The prevalence of helminth infections exhibits an inverse association with the prevalence of Type 2 diabetes mellitus (T2DM), and helminths are postulated to mediate a protective effect against T2DM. However, the biological mechanism behind this effect is not known. We postulated that helminth infec...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PLoS neglected tropical diseases 2020-03, Vol.14 (3), p.e0008101-e0008101
Hauptverfasser:	Rajamanickam, Anuradha, Munisankar, Saravanan, Dolla, Chandrakumar, Menon, Pradeep A, Thiruvengadam, Kannan, Nutman, Thomas B, Babu, Subash
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Animals Anthelmintic agents Anthelmintics - administration & dosage Antigens Antiparasitic agents Biology and Life Sciences Care and treatment CCL3 protein Chemokines Chemotherapy CXCL10 protein CXCL11 protein Cytokines Cytokines - blood Development and progression Diabetes Diabetes mellitus Diabetes mellitus (non-insulin dependent) Diabetes Mellitus, Type 2 - physiopathology Diabetes Mellitus, Type 2 - prevention & control Female Granulocyte colony-stimulating factor Granulocyte-macrophage colony-stimulating factor Health aspects Helminthiasis Humans IL-1β Infections Infectious diseases Inflammation Interleukin 1 receptor antagonist Interleukin 1 receptors Interleukin 12 Interleukin 18 Interleukin 23 Interleukin 27 Interleukin 6 Laboratories Levels Male Medical research Medicine and Health Sciences Metabolism Microscopy Middle Aged Monocyte chemoattractant protein 1 Morbidity Parasitic diseases Pathogenesis Pathogens Physical Sciences Physiological aspects Plasma levels Population Principal components analysis Research and Analysis Methods Strongyloides stercoralis - immunology Strongyloidiasis - drug therapy Strongyloidiasis - pathology Studies Therapy Tropical diseases Tuberculosis Type 2 diabetes Young Adult
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!