The association between a body shape index and cardiovascular risk in overweight and obese children and adolescents
A Body Shape Index (ABSI) and normalized hip circumference (Hip Index, HI) have been recently shown to be strong risk factors for mortality and for cardiovascular disease in adults. We conducted an observational cross-sectional study to evaluate the relationship between ABSI, HI and cardiometabolic...
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| description | A Body Shape Index (ABSI) and normalized hip circumference (Hip Index, HI) have been recently shown to be strong risk factors for mortality and for cardiovascular disease in adults. We conducted an observational cross-sectional study to evaluate the relationship between ABSI, HI and cardiometabolic risk factors and obesity-related comorbidities in overweight and obese children and adolescents aged 2-18 years. We performed multivariate linear and logistic regression analyses with BMI, ABSI, and HI age and sex normalized z scores as predictors to examine the association with cardiometabolic risk markers (systolic and diastolic blood pressure, fasting glucose and insulin, total cholesterol and its components, transaminases, fat mass % detected by bioelectrical impedance analysis) and obesity-related conditions (including hepatic steatosis and metabolic syndrome). We recruited 217 patients (114 males), mean age 11.3 years. Multivariate linear regression showed a significant association of ABSI z score with 10 out of 15 risk markers expressed as continuous variables, while BMI z score showed a significant correlation with 9 and HI only with 1. In multivariate logistic regression to predict occurrence of obesity-related conditions and above-threshold values of risk factors, BMI z score was significantly correlated to 7 out of 12, ABSI to 5, and HI to 1. Overall, ABSI is an independent anthropometric index that was significantly associated with cardiometabolic risk markers in a pediatric population affected by overweight and obesity. |
| doi_str_mv | 10.1371/journal.pone.0190426 |
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We conducted an observational cross-sectional study to evaluate the relationship between ABSI, HI and cardiometabolic risk factors and obesity-related comorbidities in overweight and obese children and adolescents aged 2-18 years. We performed multivariate linear and logistic regression analyses with BMI, ABSI, and HI age and sex normalized z scores as predictors to examine the association with cardiometabolic risk markers (systolic and diastolic blood pressure, fasting glucose and insulin, total cholesterol and its components, transaminases, fat mass % detected by bioelectrical impedance analysis) and obesity-related conditions (including hepatic steatosis and metabolic syndrome). We recruited 217 patients (114 males), mean age 11.3 years. Multivariate linear regression showed a significant association of ABSI z score with 10 out of 15 risk markers expressed as continuous variables, while BMI z score showed a significant correlation with 9 and HI only with 1. In multivariate logistic regression to predict occurrence of obesity-related conditions and above-threshold values of risk factors, BMI z score was significantly correlated to 7 out of 12, ABSI to 5, and HI to 1. Overall, ABSI is an independent anthropometric index that was significantly associated with cardiometabolic risk markers in a pediatric population affected by overweight and obesity.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0190426</identifier><identifier>PMID: 29298340</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Adolescents ; Adults ; Age ; Anthropometry ; Bioelectricity ; Biology and Life Sciences ; Blood pressure ; Blood tests ; Body fat ; Body mass index ; Body measurements ; Body weight ; Cardiovascular diseases ; Children ; Children & youth ; Cholesterol ; Comorbidity ; Continuity (mathematics) ; Correlation analysis ; Diabetes ; Expected values ; Fasting ; Fatty liver ; Health aspects ; Health risks ; Hip ; Hospitals ; Hypertension ; Insulin ; Insulin resistance ; Laboratories ; Markers ; Medicine and Health Sciences ; Metabolic disorders ; Metabolic syndrome ; Metabolism ; Methods ; Mortality ; Multivariate analysis ; Obesity ; Overweight ; Overweight persons ; Patients ; Pediatrics ; People and Places ; Population ; Regression analysis ; Risk analysis ; Risk factors ; Steatosis ; Teenagers ; Transaminases ; Triglycerides ; Ultrasonic imaging</subject><ispartof>PloS one, 2018-01, Vol.13 (1), p.e0190426-e0190426</ispartof><rights>COPYRIGHT 2018 Public Library of Science</rights><rights>2018 Mameli et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. 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In multivariate logistic regression to predict occurrence of obesity-related conditions and above-threshold values of risk factors, BMI z score was significantly correlated to 7 out of 12, ABSI to 5, and HI to 1. 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association between a body shape index and cardiovascular risk in overweight and obese children and adolescents</title><author>Mameli, Chiara ; Krakauer, Nir Y ; Krakauer, Jesse C ; Bosetti, Alessandra ; Ferrari, Chiara Matilde ; Moiana, Norma ; Schneider, Laura ; Borsani, Barbara ; Genoni, Teresa ; Zuccotti, Gianvincenzo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c692t-c3e5421d8099ff0a577f3fecdb7f6b2a854b5cf72a912c39aedf342b2c13a9273</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Adolescents</topic><topic>Adults</topic><topic>Age</topic><topic>Anthropometry</topic><topic>Bioelectricity</topic><topic>Biology and Life Sciences</topic><topic>Blood pressure</topic><topic>Blood tests</topic><topic>Body fat</topic><topic>Body mass index</topic><topic>Body measurements</topic><topic>Body weight</topic><topic>Cardiovascular 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One</addtitle><date>2018-01-03</date><risdate>2018</risdate><volume>13</volume><issue>1</issue><spage>e0190426</spage><epage>e0190426</epage><pages>e0190426-e0190426</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>A Body Shape Index (ABSI) and normalized hip circumference (Hip Index, HI) have been recently shown to be strong risk factors for mortality and for cardiovascular disease in adults. We conducted an observational cross-sectional study to evaluate the relationship between ABSI, HI and cardiometabolic risk factors and obesity-related comorbidities in overweight and obese children and adolescents aged 2-18 years. We performed multivariate linear and logistic regression analyses with BMI, ABSI, and HI age and sex normalized z scores as predictors to examine the association with cardiometabolic risk markers (systolic and diastolic blood pressure, fasting glucose and insulin, total cholesterol and its components, transaminases, fat mass % detected by bioelectrical impedance analysis) and obesity-related conditions (including hepatic steatosis and metabolic syndrome). We recruited 217 patients (114 males), mean age 11.3 years. Multivariate linear regression showed a significant association of ABSI z score with 10 out of 15 risk markers expressed as continuous variables, while BMI z score showed a significant correlation with 9 and HI only with 1. In multivariate logistic regression to predict occurrence of obesity-related conditions and above-threshold values of risk factors, BMI z score was significantly correlated to 7 out of 12, ABSI to 5, and HI to 1. Overall, ABSI is an independent anthropometric index that was significantly associated with cardiometabolic risk markers in a pediatric population affected by overweight and obesity.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>29298340</pmid><doi>10.1371/journal.pone.0190426</doi><tpages>e0190426</tpages><orcidid>https://orcid.org/0000-0002-6768-3411</orcidid><oa>free_for_read</oa></addata></record> |
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| issn | 1932-6203 1932-6203 |
| language | eng |
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| source | DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Free Full-Text Journals in Chemistry; Public Library of Science (PLoS) |
| subjects | Adolescents Adults Age Anthropometry Bioelectricity Biology and Life Sciences Blood pressure Blood tests Body fat Body mass index Body measurements Body weight Cardiovascular diseases Children Children & youth Cholesterol Comorbidity Continuity (mathematics) Correlation analysis Diabetes Expected values Fasting Fatty liver Health aspects Health risks Hip Hospitals Hypertension Insulin Insulin resistance Laboratories Markers Medicine and Health Sciences Metabolic disorders Metabolic syndrome Metabolism Methods Mortality Multivariate analysis Obesity Overweight Overweight persons Patients Pediatrics People and Places Population Regression analysis Risk analysis Risk factors Steatosis Teenagers Transaminases Triglycerides Ultrasonic imaging |
| title | The association between a body shape index and cardiovascular risk in overweight and obese children and adolescents |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-12T16%3A31%3A20IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20association%20between%20a%20body%20shape%20index%20and%20cardiovascular%20risk%20in%20overweight%20and%20obese%20children%20and%20adolescents&rft.jtitle=PloS%20one&rft.au=Mameli,%20Chiara&rft.date=2018-01-03&rft.volume=13&rft.issue=1&rft.spage=e0190426&rft.epage=e0190426&rft.pages=e0190426-e0190426&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0190426&rft_dat=%3Cgale_plos_%3EA521235055%3C/gale_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2390621678&rft_id=info:pmid/29298340&rft_galeid=A521235055&rft_doaj_id=oai_doaj_org_article_33de38e1e4a84ac7825ab53be5ae359b&rfr_iscdi=true |