Crystal structure of a UDP-GlcNAc epimerase for surface polysaccharide biosynthesis in Acinetobacter baumannii

With new strains of Acinetobacter baumannii undergoing genomic analysis, it has been possible to define regions of genomic plasticity (RGPs), encoding specific adaptive elements. For a selected RGP from a community-derived isolate of A. baumannii, we outline sequences compatible with biosynthetic ma...

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Veröffentlicht in:	PloS one 2018-01, Vol.13 (1), p.e0191610-e0191610
Hauptverfasser:	Shah, Bhumika S, Ashwood, Heather E, Harrop, Stephen J, Farrugia, Daniel N, Paulsen, Ian T, Mabbutt, Bridget C
Format:	Artikel
Sprache:	eng
Schlagworte:	Acinetobacter baumannii Antigens Biology and Life Sciences Biosynthesis Chains Chromatography Conserved sequence Crystal structure Data collection Datasets Dehydration Dimers Enzymes Epimerase Genes Genetic aspects Genomes Genomic analysis Genomics Glucosamine Glycerol Infections Lysine Medicine and Health Sciences N-Acetyl-D-glucosamine NADP Pathogens Physical Sciences Physiological aspects Polysaccharides Proteins Reductase Reductases Research and Analysis Methods Saccharides Substrates Threonine Trimers Tyrosine
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