Biological functions of the autophagy-related proteins Atg4 and Atg8 in Cryptococcus neoformans

Autophagy is a mechanism responsible for intracellular degradation and recycling of macromolecules and organelles, essential for cell survival in adverse conditions. More than 40 autophagy-related (ATG) genes have been identified and characterized in fungi, among them ATG4 and ATG8. ATG4 encodes a c...

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Veröffentlicht in:	PloS one 2020-04, Vol.15 (4), p.e0230981-e0230981
Hauptverfasser:	Roberto, Thiago Nunes, Lima, Ricardo Ferreira, Pascon, Renata Castiglioni, Idnurm, Alexander, Vallim, Marcelo Afonso
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Autophagy Biodegradation Biology and Life Sciences Bortezomib C-Terminus Cell death Cell survival Cell walls Cryptococcus neoformans Cysteine Cysteine proteinase Cystine Cytoplasm Degradation Disruption Fungal infections Fungi Gene disruption Genes Genetic engineering Macromolecules Medicine and Health Sciences Mutants Nitrogen Organelles Oxidation resistance Oxidative stress Pathogenesis Pathogens Phagocytosis Proteases Proteasome inhibitors Protein biosynthesis Proteins Research and Analysis Methods Starvation Translocation Ubiquitin Yeast Yeasts
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