Murine lupus is neutrophil elastase-independent in the MRL.Faslpr model

Loss of tolerance to nuclear antigens and multisystem tissue destruction is a hallmark of systemic lupus erythematosus (SLE). Although the source of autoantigen in lupus remains elusive, a compelling hypothetical source is dead cell debris that drives autoimmune activation. Prior reports suggest tha...

Ausführliche Beschreibung