Development and validation of a multiplex immunoassay for the simultaneous quantification of type-specific IgG antibodies to E6/E7 oncoproteins of HPV16 and HPV18

More than 170 types of human papilloma viruses (HPV) exist with many causing proliferative diseases linked to malignancy in indications such as cervical cancer and head and neck squamous cell carcinoma. Characterization of antibody levels toward HPV serology is challenging due to complex biology of...

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Veröffentlicht in:	PloS one 2020-03, Vol.15 (3), p.e0229672-e0229672
Hauptverfasser:	Layman, Hans, Rickert, Keith W, Wilson, Susan, Aksyuk, Anastasia A, Dunty, Jill M, Natrakul, Dusit, Swaminathan, Nithya, DelNagro, Christopher J
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antigen-antibody reactions Antigens Biology and life sciences Cancer Carcinogenesis Carcinoma Cervical cancer Characterization Clinical trials Compensation Cross-reactivity Dilution Diseases Dynamic range Employees Enzyme-linked immunosorbent assay Head & neck cancer Head and neck cancer Human papillomavirus Immunoassay Immunoglobulin G Immunoglobulins Malignancy Medicine and Health Sciences Methods Motor vehicle drivers Multiplexing Oncoproteins Papilloma Papillomavirus infections Pharmaceutical industry Protein purification Proteins Rankings Research and Analysis Methods Respiratory system agents Serology Squamous cell carcinoma Technology Tumorigenesis Viruses Wages & salaries
Online-Zugang:	Volltext
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