SuperFreq: Integrated mutation detection and clonal tracking in cancer

Analysing multiple cancer samples from an individual patient can provide insight into the way the disease evolves. Monitoring the expansion and contraction of distinct clones helps to reveal the mutations that initiate the disease and those that drive progression. Existing approaches for clonal trac...

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Veröffentlicht in:	PLoS computational biology 2020-02, Vol.16 (2), p.e1007603-e1007603
Hauptverfasser:	Flensburg, Christoffer, Sargeant, Tobias, Oshlack, Alicia, Majewski, Ian J
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Biology and Life Sciences Cable television broadcasting industry Cancer Cancer patients Clonal Evolution Cloning Contraction Copy number Development and progression Diseases DNA Copy Number Variations Engineering and Technology Genetic aspects Genomes Genomics Hematology Humans Integrated approach Integrated software Leukemia Medical research Medicine and Health Sciences Methods Mutation Neoplasms - genetics Nucleotides Polymorphism, Single Nucleotide Recurrence (Disease) Research and Analysis Methods Sequence analysis Setting (Literature) Supervision Tracking Tumors
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