Iron trafficking in patients with Indian Post kala-azar dermal leishmaniasis

During infections involving intracellular pathogens, iron performs a double-edged function by providing the pathogen with nutrients, but also boosts the host's antimicrobial arsenal. Although the role of iron has been described in visceral leishmaniasis, information regarding its status in the...

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Veröffentlicht in:	PLoS neglected tropical diseases 2020-02, Vol.14 (2), p.e0007991-e0007991
Hauptverfasser:	Dighal, Aishwarya, Mukhopadhyay, Debanjan, Sengupta, Ritika, Moulik, Srija, Mukherjee, Shibabrata, Roy, Susmita, Chaudhuri, Surya Jyati, Das, Nilay K, Chatterjee, Mitali
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Antigens, CD - genetics Antigens, CD - metabolism Antigens, Differentiation, Myelomonocytic - genetics Antigens, Differentiation, Myelomonocytic - metabolism Authorship Biology and Life Sciences Biopsy Care and treatment Cation Transport Proteins - genetics Cation Transport Proteins - metabolism CD14 antigen CD163 antigen Chemotherapy Circumcision Deoxyribonucleic acid Dermatology Divalent metal transporter-1 DNA ELISA Enzyme-linked immunosorbent assay Female Ferritin Flow cytometry Gene expression Glycosylated hemoglobin Haptoglobin Health aspects Heme Hemoglobin Hemoglobins Humans India Infection Iron Iron - metabolism Iron compounds Leishmania donovani - drug effects Leishmania donovani - physiology Leishmaniasis Leishmaniasis, Cutaneous - metabolism Leishmaniasis, Cutaneous - parasitology Lipocalin Lipocalin-2 - genetics Lipocalin-2 - metabolism Macrophages Macrophages - metabolism Male Medical education Medical research Medicine and Health Sciences Messenger RNA Metals Monocytes Monocytes - metabolism Nramp protein Nucleotide sequence Nutrients Oxygenase Parasites Parasitic diseases Pathogenic microorganisms Pathogens PCR Pharmacology Phenotypes Physical Sciences Pigments Plasma Receptors Receptors, Cell Surface - genetics Receptors, Cell Surface - metabolism Receptors, Transferrin - genetics Receptors, Transferrin - metabolism RNA Scavenging Skin Software Transferrin Transferrins Tropical diseases Vector-borne diseases Visceral leishmaniasis Young Adult
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