Myosoft: An automated muscle histology analysis tool using machine learning algorithm utilizing FIJI/ImageJ software

Muscle sections were stained for cell boundary (laminin) and myofiber type (myosin heavy chain isoforms). Myosoft, running in the open access software platform FIJI (ImageJ), was used to analyze myofiber size and type in transverse sections of entire gastrocnemius/soleus muscles. Myosoft provides an...

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Veröffentlicht in:	PloS one 2020-03, Vol.15 (3), p.e0229041-e0229041
Hauptverfasser:	Encarnacion-Rivera, Lucas, Foltz, Steven, Hartzell, H Criss, Choo, Hyojung
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Algorithms Anatomy, Cross-Sectional - methods Animals Antibodies Automation Biology Biology and Life Sciences Cell Size Computer and Information Sciences Computer programs Data mining Diseases Economic indicators Fluorescence High-Throughput Screening Assays - methods Histological Techniques - methods Histology Image Processing, Computer-Assisted - methods Image quality Isoforms Laminin Learning algorithms Machine Learning Medicine Medicine and Health Sciences Metabolism Methods Mice Mice, Inbred C57BL Mice, Transgenic Muscle contraction Muscle Fibers, Skeletal - cytology Muscle Fibers, Skeletal - pathology Muscle function Muscle proteins Muscle, Skeletal - cytology Muscle, Skeletal - pathology Muscles Musculoskeletal system Myopathy Myosin Neural networks Novels Open access Physiological aspects Physiology Reproducibility of Results Research and Analysis Methods Skeletal muscle Software Time Watersheds
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