Expression of the muscle-associated gene MYF6 in hairy cell leukemia

Hairy cell leukemia (HCL) is a purine analog-responsive B-cell malignancy containing the BRAF V600E mutation, expressing CD22, CD11c, CD103, tartrate resistant acid phosphatase (TRAP) CD25, CD123, and annexin 1A. BRAF V600E and the latter 4 markers are usually absent in the more aggressive and chemo...

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Veröffentlicht in:	PloS one 2020-02, Vol.15 (2), p.e0227586-e0227586
Hauptverfasser:	Arons, Evgeny, Zhou, Hong, Sokolsky, Mark, Gorelik, Daniel, Potocka, Katherine, Davies, Sarah, Fykes, Erin, Still, Katherine, Edelman, Daniel C, Wang, Yonghong, Meltzer, Paul S, Raffeld, Mark, Wiestner, Adrian, Xi, Liqiang, Wang, Hao-Wei, Stetler-Stevenson, Maryalice, Yuan, Constance, Kreitman, Robert J
Format:	Artikel
Sprache:	eng
Schlagworte:	Acid phosphatase Acid phosphatase (tartrate-resistant) Acid resistance Adult Aged Alkaloids B cells Biology and Life Sciences Biomarkers Biotechnology industries Blood Blood donation Blood donors Cancer Cancer genetics CD103 antigen CD11c antigen CD123 antigen CD22 antigen CD25 antigen Chronic lymphocytic leukemia Consent DNA Methylation - genetics DNA microarrays EDTA Female Flow cytometry Gene expression Gene Expression Profiling Gene Expression Regulation, Leukemic Gene mutation Genes Genetic aspects Hairy cell leukemia Humans Laboratories Leukemia Leukemia, Hairy Cell - genetics Leukemia, Lymphocytic, Chronic, B-Cell - genetics Limit of Detection Lymphatic leukemia Lymphocytes B Lymphocytic leukemia Lymphoma Lymphomas Male Malignancy Mantle cell lymphoma Medical prognosis Medicine and Health Sciences Middle Aged Molecular biology Muscles Muscles - metabolism Musculoskeletal system Mutation Myogenic Regulatory Factors - genetics Myogenic Regulatory Factors - metabolism Neoplasm, Residual - genetics Neoplasm, Residual - pathology Pathology Phosphatases Polymerase chain reaction Probes Research and Analysis Methods Time Tumors
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